TAS2R40

Taste receptor type 2 member 40 is a protein that in humans is encoded by the TAS2R40 gene.[5][6]

TAS2R40
Identifiers
Aliases	TAS2R40, GPR60, T2R40, T2R58, taste 2 receptor member 40
External IDs	OMIM: 613964 MGI: 2681312 HomoloGene: 47977 GeneCards: TAS2R40
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q34 Start 143,222,037 bp[1] End 143,223,079 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 B2.1 Start 42,215,328 bp[2] End 42,216,287 bp[2]
Gene ontology Molecular function • G-protein coupled receptor activity • signal transducer activity • bitter taste receptor activity Cellular component • cell membrane • membrane • integral component of membrane Biological process • detection of chemical stimulus involved in sensory perception of bitter taste • signal transduction • response to stimulus • sensory perception of taste • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	259286	387515
Ensembl	ENSG00000221937	ENSMUSG00000051917
UniProt	P59535	Q7TQB8
RefSeq (mRNA)	NM_176882	NM_001001453
RefSeq (protein)	NP_795363	NP_001001453
Location (UCSC)	Chr 7: 143.22 – 143.22 Mb	Chr 6: 42.22 – 42.22 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• Taste receptor

References

1. GRCh38: Ensembl release 89: ENSG00000221937 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051917 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (Oct 2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855.
6. "Entrez Gene: TAS2R40 taste receptor, type 2, member 40".

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520.
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.