GPR87

Probable G-protein coupled receptor 87 is a protein that in humans is encoded by the GPR87 gene.[5][6]

GPR87
Identifiers
Aliases	GPR87, GPR95, KPG_002, FKSG78, G protein-coupled receptor 87
External IDs	OMIM: 606379 MGI: 1934133 HomoloGene: 13021 GeneCards: GPR87
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3q25.1 Start 151,294,086 bp[1] End 151,316,820 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 D Start 59,178,923 bp[2] End 59,195,104 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled purinergic nucleotide receptor activity • G-protein coupled receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • integral component of plasma membrane • membrane Biological process • G-protein coupled receptor signaling pathway • negative regulation of adenylate cyclase activity • signal transduction • G-protein coupled purinergic nucleotide receptor signaling pathway • biological process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	53836	84111
Ensembl	ENSG00000138271	ENSMUSG00000051431
UniProt	Q9BY21	Q99MT7
RefSeq (mRNA)	NM_023915	NM_001302203 NM_032399
RefSeq (protein)	NP_076404	NP_001289132
Location (UCSC)	Chr 3: 151.29 – 151.32 Mb	Chr 3: 59.18 – 59.2 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

G protein-coupled receptors play a role in cell communication. They are characterized by an extracellular N terminus, 7 transmembrane regions, and an intracellular C terminus.[supplied by OMIM][6]

References

1. GRCh38: Ensembl release 89: ENSG00000138271 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000051431 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Wittenberger T, Schaller HC, Hellebrand S (Mar 2001). "An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors". J Mol Biol. 307 (3): 799–813. doi:10.1006/jmbi.2001.4520. PMID 11273702.
6. "Entrez Gene: GPR87 G protein-coupled receptor 87".

Further reading

• Lee DK, Nguyen T, Lynch KR, et al. (2001). "Discovery and mapping of ten novel G protein-coupled receptor genes". Gene. 275 (1): 83–91. doi:10.1016/S0378-1119(01)00651-5. PMID 11574155.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.