GPR85

Probable G-protein coupled receptor 85 is a protein that in humans is encoded by the GPR85 gene.[5][6][7]

GPR85
Identifiers
Aliases	GPR85, SREB, SREB2, G protein-coupled receptor 85
External IDs	OMIM: 605188 MGI: 1927851 HomoloGene: 10355 GeneCards: GPR85
Gene location (Human) Chr. Chromosome 7 (human)[1] Band 7q31.1 Start 113,078,331 bp[1] End 113,087,778 bp[1]
Gene location (Mouse) Chr. Chromosome 6 (mouse)[2] Band 6|6 A1 Start 13,834,458 bp[2] End 13,839,942 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • G-protein coupled receptor activity • GO:0001948 protein binding • signal transducer activity Cellular component • integral component of membrane • endoplasmic reticulum • membrane • cell membrane Biological process • G-protein coupled receptor signaling pathway • signal transduction Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54329	64450
Ensembl	ENSG00000164604	ENSMUSG00000048216
UniProt	P60893	P60894
RefSeq (mRNA)	NM_001146265 NM_001146266 NM_001146267 NM_018970	NM_145066 NM_001330666 NM_001330667
RefSeq (protein)	NP_001139737 NP_001139738 NP_001139739 NP_061843	NP_001317595 NP_001317596 NP_659503
Location (UCSC)	Chr 7: 113.08 – 113.09 Mb	Chr 6: 13.83 – 13.84 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• SREB

References

1. GRCh38: Ensembl release 89: ENSG00000164604 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000048216 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Hellebrand S, Schaller HC, Wittenberger T (Nov 2000). "The brain-specific G-protein coupled receptor GPR85 with identical protein sequence in man and mouse maps to human chromosome 7q31". Biochim Biophys Acta. 1493 (1–2): 269–72. doi:10.1016/s0167-4781(00)00182-2. PMID 10978537.
6. Matsumoto M, Saito T, Takasaki J, Kamohara M, Sugimoto T, Kobayashi M, Tadokoro M, Matsumoto S, Ohishi T, Furuichi K (Jul 2000). "An evolutionarily conserved G-protein coupled receptor family, SREB, expressed in the central nervous system". Biochem Biophys Res Commun. 272 (2): 576–82. doi:10.1006/bbrc.2000.2829. PMID 10833454.
7. "Entrez Gene: GPR85 G protein-coupled receptor 85".

Further reading

• "Toward a complete human genome sequence". Genome Res. 8 (11): 1097–108. 1999. doi:10.1101/gr.8.11.1097. PMID 9847074.
• Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
• Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
• Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Jeon J, Kim C, Sun W, et al. (2002). "Cloning and localization of rgpr85 encoding rat G-protein-coupled receptor". Biochem. Biophys. Res. Commun. 298 (4): 613–8. doi:10.1016/S0006-291X(02)02515-9. PMID 12408996.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hillier LW, Fulton RS, Fulton LA, et al. (2003). "The DNA sequence of human chromosome 7". Nature. 424 (6945): 157–64. doi:10.1038/nature01782. PMID 12853948.
• Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Matsumoto M, Beltaifa S, Weickert CS, et al. (2005). "A conserved mRNA expression profile of SREB2 (GPR85) in adult human, monkey, and rat forebrain". Brain Res. Mol. Brain Res. 138 (1): 58–69. doi:10.1016/j.molbrainres.2005.04.002. PMID 15893849.
• Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
• Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.