Monokine

A monokine is a type of cytokine[1] produced primarily by monocytes and macrophages.

Some monokines are:

  • interleukin 1 [2]
  • tumor necrosis factor-alpha [2]
  • alpha and beta interferon [3]
  • colony stimulating factors [3]

Functions

Monokines released from macrophages can attract neutrophils, via the process chemotaxis.

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See also

References
  1. Monokines at the US National Library of Medicine Medical Subject Headings (MeSH)
  2. Leung DY, Geha RS, Newburger JW (1986). "Two monokines, interleukin 1 and tumor necrosis factor, render cultured vascular endothelial cells susceptible to lysis by antibodies circulating during Kawasaki syndrome". The Journal of Experimental Medicine. 164 (6): 1958–72. doi:10.1084/jem.164.6.1958. PMC 2188474. PMID 3491174.
  3. Julius M. Cruse; Robert Edwin Lewis (20 April 2009). Illustrated dictionary of immunology. CRC Press. pp. 208–. ISBN 978-0-8493-7987-1. Retrieved 24 April 2011.


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