HSPA4L

Heat shock 70 kDa protein 4L is a protein that in humans is encoded by the HSPA4L gene.[5][6]

HSPA4L
Identifiers
Aliases	HSPA4L, APG-1, HSPH3, Osp94, heat shock protein family A (Hsp70) member 4 like
External IDs	MGI: 107422 HomoloGene: 22610 GeneCards: HSPA4L
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q28.1 Start 127,781,821 bp[1] End 127,840,733 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 B Start 40,744,495 bp[2] End 40,796,103 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleotide binding • ATP binding Cellular component • cytoplasm • cytosol • cell nucleus Biological process • response to unfolded protein • protein folding Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	22824	18415
Ensembl	ENSG00000164070	ENSMUSG00000025757
UniProt	O95757	P48722
RefSeq (mRNA)	NM_014278 NM_001317381 NM_001317382 NM_001317383	NM_011020
RefSeq (protein)	NP_001304310 NP_001304311 NP_001304312 NP_055093	NP_035150
Location (UCSC)	Chr 4: 127.78 – 127.84 Mb	Chr 3: 40.74 – 40.8 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000164070 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000025757 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nonoguchi K, Itoh K, Xue JH, Tokuchi H, Nishiyama H, Kaneko Y, Tatsumi K, Okuno H, Tomiwa K, Fujita J (Nov 1999). "Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes". Gene. 237 (1): 21–8. doi:10.1016/S0378-1119(99)00325-X. PMID 10524232.
6. "Entrez Gene: HSPA4L heat shock 70kDa protein 4-like".

Further reading

• Nonoguchi K, Tokuchi H, Okuno H, Watanabe H, Egawa H, Saito K, Ogawa O, Fujita J (2001). "Expression of Apg-1, a member of the Hsp110 family, in the human testis and sperm". Int. J. Urol. 8 (6): 308–14. doi:10.1046/j.1442-2042.2001.00304.x. PMID 11389747.
• Matsumori M, Itoh H, Toyoshima I, Komatsuda A, Sawada K, Fukuda J, Tanaka T, Okubo A, Kinouchi H, Mizoi K, Hama T, Suzuki A, Hamada F, Otaka M, Shoji Y, Takada G (2003). "Characterization of the 105-kDa molecular chaperone. Identification, biochemical properties, and localization". Eur. J. Biochem. 269 (22): 5632–41. doi:10.1046/j.1432-1033.2002.03272.x. PMID 12423363.
• Colgan SP, Pitman RS, Nagaishi T, Mizoguchi A, Mizoguchi E, Mayer LF, Shao L, Sartor RB, Subjeck JR, Blumberg RS (2003). "Intestinal heat shock protein 110 regulates expression of CD1d on intestinal epithelial cells". J. Clin. Invest. 112 (5): 745–54. doi:10.1172/JCI17241. PMC 182184. PMID 12952923.
• Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.

External links

• HSPA4L+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)