60S ribosomal protein L10-like

60S ribosomal protein L10-like is a protein that in humans is encoded by the RPL10L gene.[5][6]

RPL10L
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4UG0, 4V6X
Identifiers
Aliases	RPL10L, RPL10_5_1358, ribosomal protein L10 like
External IDs	MGI: 3647985 HomoloGene: 68830 GeneCards: RPL10L
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q21.2 Start 46,651,010 bp[1] End 46,651,781 bp[1]
Gene location (Mouse) Chr. Chromosome 12 (mouse)[2] Band 12|12 C2 Start 66,283,379 bp[2] End 66,284,401 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • structural constituent of ribosome • RNA binding Cellular component • polysome • cytosolic large ribosomal subunit • ribosome • intracellular • membrane • cell nucleus • endoplasmic reticulum • cytosol Biological process • protein biosynthesis • ribosomal large subunit assembly • spermatogenesis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	140801	238217
Ensembl	ENSG00000165496	ENSMUSG00000060499
UniProt	Q96L21	P86048
RefSeq (mRNA)	NM_080746	NM_001162933
RefSeq (protein)	NP_542784	NP_001156405
Location (UCSC)	Chr 14: 46.65 – 46.65 Mb	Chr 12: 66.28 – 66.28 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Function

This gene encodes a protein sharing sequence similarity with ribosomal protein L10 (RPL10). It is not currently known whether the encoded protein is a functional ribosomal protein or whether it has evolved a function that is independent of the ribosome. This gene is intronless.[6]

References

1. GRCh38: Ensembl release 89: ENSG00000165496 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000060499 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Balasubramanian S, Zheng D, Liu YJ, Fang G, Frankish A, Carriero N, Robilotto R, Cayting P, Gerstein M (May 2009). "Comparative analysis of processed ribosomal protein pseudogenes in four mammalian genomes". Genome Biology. 10 (1): R2. doi:10.1186/gb-2009-10-1-r2. PMC 2687790. PMID 19123937.
6. "Entrez Gene: RPL10L ribosomal protein L10-like".

Further reading

• Mehrle A, Rosenfelder H, Schupp I, del Val C, Arlt D, Hahne F, Bechtel S, Simpson J, Hofmann O, Hide W, Glatting KH, Huber W, Pepperkok R, Poustka A, Wiemann S (January 2006). "The LIFEdb database in 2006". Nucleic Acids Research. 34 (Database issue): D415-8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
• Wiemann S, Arlt D, Huber W, Wellenreuther R, Schleeger S, Mehrle A, Bechtel S, Sauermann M, Korf U, Pepperkok R, Sültmann H, Poustka A (October 2004). "From ORFeome to biology: a functional genomics pipeline". Genome Research. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
• Uechi T, Maeda N, Tanaka T, Kenmochi N (December 2002). "Functional second genes generated by retrotransposition of the X-linked ribosomal protein genes". Nucleic Acids Research. 30 (24): 5369–75. doi:10.1093/nar/gkf696. PMC 140079. PMID 12490704.
• Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (September 2000). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Reports. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
• Hartley JL, Temple GF, Brasch MA (November 2000). "DNA cloning using in vitro site-specific recombination". Genome Research. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.

External links

• Overview of all the structural information available in the PDB for UniProt: Q96L21 (Human 60S ribosomal protein L10-like) at the PDBe-KB.