mir-156 microRNA precursor

MicroRNA (miRNA) precursor miR156 is a family of plant non-coding RNA. This microRNA has now been predicted or experimentally confirmed in a range of plant species (MIPF0000008). Animal miRNAs are transcribed as ~70 nucleotide precursors and subsequently processed by the Dicer enzyme to give a ~22 nucleotide product. In plants the precursor sequences may be longer, and the carpel factory (caf) enzyme appears to be involved in processing. In this case the mature sequence comes from the 5' arm of the precursor, and both Arabidopsis thaliana and rice genomes contain a number of related miRNA precursors which give rise to almost identical mature sequences. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA.

miR156 microRNA precursor
Predicted secondary structure and sequence conservation of mir-156
Identifiers
SymbolmiR156
RfamRF00073
miRBaseMI0000178
miRBase familyMIPF0000008
Other data
RNA typeGene; miRNA
Domain(s)Eukaryota
GO0035195 0035068
SO0001244
PDB structuresPDBe

This miRNA is involved in control of reproductive structures in liverworts.[1]

References
  1. Tsuzuki, Masayuki; Futagami, Kazutaka; Shimamura, Masaki; Inoue, Chikako; Kunimoto, Kan; Oogami, Takashi; Tomita, Yuki; Inoue, Keisuke; Kohchi, Takayuki; Yamaoka, Shohei; Araki, Takashi; Hamada, Takahiro; Watanabe, Yuichiro (2019). "An Early Arising Role of the MicroRNA156/529-SPL Module in Reproductive Development Revealed by the Liverwort Marchantia polymorpha". Current Biology. doi:10.1016/j.cub.2019.07.084. ISSN 0960-9822.

Further reading

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