MYO1B

Myosin-Ib is a protein that in humans is encoded by the MYO1B gene.[5][6][7]

MYO1B
Identifiers
Aliases	MYO1B, myr1, myosin IB, MMIa, MMI-alpha, MYH-1c
External IDs	OMIM: 606537 MGI: 107752 HomoloGene: 7856 GeneCards: MYO1B
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q32.3 Start 191,245,185 bp[1] End 191,425,389 bp[1]
Gene location (Mouse) Chr. Chromosome 1 (mouse)[2] Band 1 C1.1|1 26.58 cM Start 51,749,765 bp[2] End 51,916,071 bp[2]
Gene ontology Molecular function • nucleotide binding • actin-dependent ATPase activity • calmodulin binding • microfilament motor activity • actin binding • phosphatidylinositol-4,5-bisphosphate binding • cellular motor activity • ATP binding • phosphatidylinositol-3,4,5-trisphosphate binding • actin filament binding • cadherin binding Cellular component • cytoplasm • trans-Golgi network membrane • filopodium • early endosome • brush border • actin filament • perinuclear region of cytoplasm • endosome membrane • extracellular exosome • cell periphery • myosin complex • cell membrane • apical part of cell Biological process • actin filament organization • actin filament-based movement • actin filament bundle assembly • post-Golgi vesicle-mediated transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	4430	17912
Ensembl	ENSG00000128641	ENSMUSG00000018417
UniProt	O43795	P46735
RefSeq (mRNA)	NM_001130158 NM_001161819 NM_012223 NM_001330237 NM_001330238	NM_001161817 NM_001290982 NM_010863
RefSeq (protein)	NP_001123630 NP_001155291 NP_001317166 NP_001317167 NP_036355	NP_001155289 NP_001277911 NP_034993
Location (UCSC)	Chr 2: 191.25 – 191.43 Mb	Chr 1: 51.75 – 51.92 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000128641 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000018417 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Bement WM, Hasson T, Wirth JA, Cheney RE, Mooseker MS (Aug 1994). "Identification and overlapping expression of multiple unconventional myosin genes in vertebrate cell types". Proc Natl Acad Sci U S A. 91 (14): 6549–53. doi:10.1073/pnas.91.14.6549. PMC 44240. PMID 8022818.
6. Ruppert C, Kroschewski R, Bahler M (Apr 1993). "Identification, characterization and cloning of myr 1, a mammalian myosin-I". J Cell Biol. 120 (6): 1393–403. doi:10.1083/jcb.120.6.1393. PMC 2119751. PMID 8449985.
7. "Entrez Gene: MYO1B myosin IB".

Further reading

• Ruppert C, Godel J, Müller RT, et al. (1997). "Localization of the rat myosin I molecules myr 1 and myr 2 and in vivo targeting of their tail domains". J. Cell Sci. 108 (12): 3775–86. PMID 8719884.
• Tang N, Ostap EM (2001). "Motor domain-dependent localization of myo1b (myr-1)". Curr. Biol. 11 (14): 1131–5. doi:10.1016/S0960-9822(01)00320-7. PMID 11509238.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dumont RA, Zhao YD, Holt JR, et al. (2003). "Myosin-I isozymes in neonatal rodent auditory and vestibular epithelia". J. Assoc. Res. Otolaryngol. 3 (4): 375–89. doi:10.1007/s101620020049. PMC 3202438. PMID 12486594.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Salas-Cortes L, Ye F, Tenza D, et al. (2006). "Myosin Ib modulates the morphology and the protein transport within multi-vesicular sorting endosomes". J. Cell Sci. 118 (Pt 20): 4823–32. doi:10.1242/jcs.02607. PMID 16219689.
• Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein–protein interactions by mass spectrometry". Mol. Syst. Biol. 3 (1): 89. doi:10.1038/msb4100134. PMC 1847948. PMID 17353931.