MYO1F

Myosin-If is a protein that in humans is encoded by the MYO1F gene.[5][6][7]

MYO1F
Identifiers
AliasesMYO1F, myosin IF
External IDsOMIM: 601480 MGI: 107711 HomoloGene: 56276 GeneCards: MYO1F
Gene location (Human)
Chr.Chromosome 19 (human)[1]
Band19p13.2Start8,520,778 bp[1]
End8,577,577 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

4542

17916

Ensembl

ENSG00000142347

ENSMUSG00000024300

UniProt

O00160

P70248

RefSeq (mRNA)

NM_012335
NM_001348355

NM_053214

RefSeq (protein)

NP_036467
NP_001335284

n/a

Location (UCSC)Chr 19: 8.52 – 8.58 MbChr 17: 33.56 – 33.61 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

It is expressed mainly in the immune system and might be involved in cell adhesion and motility.[8] It is a candidate gene for (among other things) nonsyndromic deafness.[9]

References

  1. GRCh38: Ensembl release 89: ENSG00000142347 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000024300 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Crozet F, el Amraoui A, Blanchard S, Lenoir M, Ripoll C, Vago P, Hamel C, Fizames C, Levi-Acobas F, Depetris D, Mattei MG, Weil D, Pujol R, Petit C (Apr 1997). "Cloning of the genes encoding two murine and human cochlear unconventional type I myosins". Genomics. 40 (2): 332–41. doi:10.1006/geno.1996.4526. PMID 9119401.
  6. Hasson T, Skowron JF, Gilbert DJ, Avraham KB, Perry WL, Bement WM, Anderson BL, Sherr EH, Chen ZY, Greene LA, Ward DC, Corey DP, Mooseker MS, Copeland NG, Jenkins NA (Feb 1997). "Mapping of unconventional myosins in mouse and human". Genomics. 36 (3): 431–9. doi:10.1006/geno.1996.0488. PMID 8884266.
  7. "Entrez Gene: MYO1F myosin IF".
  8. Kim SV, Mehal WZ, Dong X, Heinrich V, Pypaert M, Mellman I, Dembo M, Mooseker MS, Wu D, Flavell RA (October 2006). "Modulation of cell adhesion and motility in the immune system by Myo1f". Science. 314 (5796): 136–9. doi:10.1126/science.1131920. PMID 17023661.
  9. Chen AH, Stephan DA, Hasson T, Fukushima K, Nelissen CM, Chen AF, Jun AI, Ramesh A, Van Camp G, Smith RJ (August 2001). "MYO1F as a candidate gene for nonsyndromic deafness, DFNB15". Arch. Otolaryngol. Head Neck Surg. 127 (8): 921–5. doi:10.1001/archotol.127.8.921. PMID 11493199.

Further reading


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