Hexestrol dipropionate

Hexestrol dipropionate (brand name Hexanoestrol, Retalon Oleosum), or hexestrol dipropanoate, is a synthetic, nonsteroidal estrogen of the stilbestrol group related to diethylstilbestrol.[1] It is an ester of hexestrol,[1] and has been known since at least 1931.[2] The drug has been used in the past to inhibit lactation in women.[3][4]

Parenteral potencies and durations of nonsteroidal estrogens
EstrogenFormMajor brand name(s)EPD (14 days)Duration
Diethylstilbestrol (DES)Oil solutionMetestrol20 mg1 mg ≈ 2–3 days; 3 mg ≈ 3 days
Diethylstilbestrol dipropionateOil solutionCyren B12.5–15 mg2.5 mg ≈ 5 days
Aqueous suspension?5 mg? mg = 21–28 days
Dimestrol (DES dimethyl ether)Oil solutionDepot-Cyren, Depot-Oestromon, Retalon Retard20–40 mg?
Fosfestrol (DES diphosphate)aAqueous solutionHonvan?<1 day
Dienestrol diacetateAqueous suspensionFarmacyrol-Kristallsuspension50 mg?
Hexestrol dipropionateOil solutionHormoestrol, Retalon Oleosum25 mg?
Hexestrol diphosphateaAqueous solutionCytostesin, Pharmestrin, Retalon Aquosum?Very short
Note: All by intramuscular injection unless otherwise noted. Footnotes: a = By intravenous injection. Sources: See template.
Hexestrol dipropionate
Clinical data
Other namesHexestrol 4,4'-dipropionate
Identifiers
CAS Number
PubChem CID
ChemSpider
ChEMBL
Chemical and physical data
FormulaC24H30O4
Molar mass382.500 g·mol−1
3D model (JSmol)

See also

References

  1. J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 163. doi:10.1007/978-1-4757-2085-3. ISBN 978-1-4757-2085-3. OCLC 898564124.
  2. Report. U.S. Government Printing Office. 1931. p. 104. LCCN sn85063598.
  3. Quarterly Review of Obstetrics and Gynecology. Washington Institute of Medicine. 1944. p. 714. ISSN 0096-9230. OCLC 1763253.
  4. Journal of Clinical Endocrinology. Charles C. Thomas. 1945. p. 194. ISSN 0368-1610. LCCN 45029631. OCLC 1607514.


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