Estradiol hemisuccinate
Estradiol hemisuccinate (brand name Eutocol), or simply estradiol succinate, also known as estradiol 17β-hemisuccinate, is an estrogen medication and an estrogen ester – specifically, the hemisuccinate ester of estradiol.[1] It is used as a component of hormone replacement therapy for menopause.[2] Like other estrogens, estradiol hemisuccinate has been found to have beneficial effects on the skin, with improvement of skin thickness observed.[3][4]
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| Trade names | Eutocol, Hosterona (with progesterone) |
| Other names | Estradiol succinate; Estradiol 17β-hemisuccinate; Estradiol 17β-succinate |
| Routes of administration | By mouth, intramuscular injection |
| Drug class | Estrogen; Estrogen ester |
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| ECHA InfoCard | 100.163.857  |
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| Formula | C22H28O5 |
| Molar mass | 372.461 g·mol−1 |
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Estradiol hemisuccinate is also a component of estradiol hemisuccinate/progesterone (brand name Hosterona), an injectable preparation used to induce withdrawal bleeding in women with amenorrhea.[5][6][7]
See also
References
- J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. p. 897. ISBN 978-1-4757-2085-3.
- Miranda A. Farage; Kenneth W. Miller; Howard I. Maibach (2 December 2009). Textbook of Aging Skin. Springer Science & Business Media. pp. 362–. ISBN 978-3-540-89655-5.
- Thompson, Zack; Maibach, Howard I. (2010). "Biological Effects of Estrogen on Skin": 361–367. doi:10.1007/978-3-540-89656-2_35. Cite journal requires
|journal=(help) - Maheux R, Naud F, Rioux M, Grenier R, Lemay A, Guy J, Langevin M (1994). "A randomized, double-blind, placebo-controlled study on the effect of conjugated estrogens on skin thickness". Am. J. Obstet. Gynecol. 170 (2): 642–9. doi:10.1016/s0002-9378(94)70242-x. PMID 8116726.
- https://matchmyrx.com/es/directorio/marca/hosterona
- https://www.losmedicamentos.net/medicamento/hosterona
- http://py.mivademecum.com/medicamento-hosterona-id-23974
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