CEP72

Centrosomal protein of 72 kDa is a protein that in humans is encoded by the CEP72 gene.[5][6]

CEP72
Identifiers
Aliases	CEP72, centrosomal protein 72
External IDs	OMIM: 616475 MGI: 1921720 HomoloGene: 10027 GeneCards: CEP72
Gene location (Human) Chr. Chromosome 5 (human)[1] Band 5p15.33 Start 612,340 bp[1] End 667,168 bp[1]
Gene location (Mouse) Chr. Chromosome 13 (mouse)[2] Band 13|13 C1 Start 74,036,500 bp[2] End 74,062,299 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • GO:0001948 protein binding • identical protein binding Cellular component • cytoplasm • microtubule organizing center • cytosol • centrosome • centriolar satellite • cytoskeleton Biological process • gamma-tubulin complex localization • centriole replication • GO:0043146 spindle organization • G2/M transition of mitotic cell cycle • regulation of protein localization to centrosome • ciliary basal body docking • regulation of G2/M transition of mitotic cell cycle Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	55722	74470
Ensembl	ENSG00000280688 ENSG00000112877	ENSMUSG00000021572
UniProt	Q9P209	Q9D3R3
RefSeq (mRNA)	NM_018140	NM_028959
RefSeq (protein)	NP_060610	NP_083235
Location (UCSC)	Chr 5: 0.61 – 0.67 Mb	Chr 13: 74.04 – 74.06 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

The product of this gene is a member of the Leucine-rich repeat (LRR) superfamily of proteins. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.[6]

References

1. ENSG00000112877 GRCh38: Ensembl release 89: ENSG00000280688, ENSG00000112877 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000021572 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nagase T, Kikuno R, Ishikawa K, Hirosawa M, Ohara O (Sep 2000). "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 7 (2): 143–50. doi:10.1093/dnares/7.2.143. PMID 10819331.
6. "Entrez Gene: CEP72 centrosomal protein 72kDa".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
• Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Andersen JS, Wilkinson CJ, Mayor T, et al. (2003). "Proteomic characterization of the human centrosome by protein correlation profiling". Nature. 426 (6966): 570–4. doi:10.1038/nature02166. PMID 14654843.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

External links

• Human CEP72 genome location and CEP72 gene details page in the UCSC Genome Browser.