COPZ1

Coatomer subunit zeta-1 is a protein that in humans is encoded by the COPZ1 gene.[5]

COPZ1
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesCOPZ1, COPZ, HSPC181, zeta-COP, zeta1-COP, CGI-120, coatomer protein complex subunit zeta 1, COPI coat complex subunit zeta 1
External IDsOMIM: 615472 MGI: 1929063 HomoloGene: 9366 GeneCards: COPZ1
Gene location (Human)
Chr.Chromosome 12 (human)[1]
Band12q13.13Start54,301,202 bp[1]
End54,351,846 bp[1]
RNA expression pattern
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez

22818

56447

Ensembl

ENSG00000111481

ENSMUSG00000060992

UniProt

P61923

P61924

RefSeq (mRNA)

NM_001271734
NM_001271735
NM_001271736
NM_016057

NM_019817
NM_001357748

RefSeq (protein)

NP_001258663
NP_001258664
NP_001258665
NP_057141

NP_062791
NP_001344677

Location (UCSC)Chr 12: 54.3 – 54.35 MbChr 15: 103.27 – 103.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

COPZ1 has been shown to interact with COPG.[6][7]

gollark: If the software updates are made on a different continent and you can apply them in less than about 50ms, you don't even need the time travel - just transmit them directly to your computer via a trans-crustal neutrino beam. Neutrinos travel only very slightly slower than light, and can take a more direct path because they don't interact much with matter, while the fibre-optic lines for internet traffic only let light go at 0.6c or something, and use less direct paths, and have routing overhead.
gollark: You did not specify that they were stolen from evil people, and possibly yes.
gollark: I'm not an EVILDOER!!!!!
gollark: See, it's important to download and install security patches as soon as possible to minimize the amount of time you go around with insecure software with vulnerabilities now known to everyone. But my internet connection is slow. So the solution is simple - download the software updates after release, then send them back in time to a few hours before release and apply them then.
gollark: The osmarks.tk closed timelike curve has a lot of spare capacity, we mostly use it to speed up software updates.

References

  1. GRCh38: Ensembl release 89: ENSG00000111481 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000060992 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: COPZ1 coatomer protein complex, subunit zeta 1".
  6. Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (November 2000). "Identification and characterization of novel isoforms of COP I subunits". J. Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.
  7. Faulstich D, Auerbach S, Orci L, Ravazzola M, Wegchingel S, Lottspeich F, Stenbeck G, Harter C, Wieland FT, Tschochner H (Oct 1996). "Architecture of coatomer: molecular characterization of delta-COP and protein interactions within the complex" (PDF). J. Cell Biol. 135 (1): 53–61. doi:10.1083/jcb.135.1.53. PMC 2121028. PMID 8858162.

Further reading


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