AP3B2

AP-3 complex subunit beta-2 is a protein that in humans is encoded by the AP3B2 gene.[5][6][7]

AP3B2
Identifiers
Aliases	AP3B2, NAPTB, adaptor related protein complex 3 beta 2 subunit, EIEE48, adaptor related protein complex 3 subunit beta 2
External IDs	OMIM: 602166 MGI: 1100869 HomoloGene: 55837 GeneCards: AP3B2
Gene location (Human) Chr. Chromosome 15 (human)[1] Band 15q25.2 Start 82,659,281 bp[1] End 82,709,946 bp[1]
Gene location (Mouse) Chr. Chromosome 7 (mouse)[2] Band 7 D3|7 45.71 cM Start 81,460,399 bp[2] End 81,493,925 bp[2]
Gene ontology Molecular function • transporter activity Cellular component • AP-3 adaptor complex • membrane coat • cytoplasmic vesicle • clathrin-coated vesicle membrane • membrane • COPI-coated vesicle • axon cytoplasm • Golgi apparatus • intracellular vesicle Biological process • anterograde axonal transport • protein transport • anterograde synaptic vesicle transport • intracellular protein transport • vesicle-mediated transport • post-Golgi vesicle-mediated transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	8120	11775
Ensembl	ENSG00000103723	ENSMUSG00000062444
UniProt	Q13367	Q9JME5
RefSeq (mRNA)	NM_001278511 NM_001278512 NM_004644 NM_001348440 NM_001348441	NM_021492 NM_146192
RefSeq (protein)	NP_001265440 NP_001265441 NP_004635 NP_001335369 NP_001335370	NP_067467
Location (UCSC)	Chr 15: 82.66 – 82.71 Mb	Chr 7: 81.46 – 81.49 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000103723 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000062444 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Newman LS, McKeever MO, Okano HJ, Darnell RB (Oct 1995). "Beta-NAP, a cerebellar degeneration antigen, is a neuron-specific vesicle coat protein". Cell. 82 (5): 773–83. doi:10.1016/0092-8674(95)90474-3. PMID 7671305.
6. Darnell RB, Furneaux HM, Posner JB (Jun 1991). "Antiserum from a patient with cerebellar degeneration identifies a novel protein in Purkinje cells, cortical neurons, and neuroectodermal tumors". J Neurosci. 11 (5): 1224–30. PMID 1851215.
7. "Entrez Gene: AP3B2 adaptor-related protein complex 3, beta 2 subunit".

External links

• Human AP3B2 genome location and AP3B2 gene details page in the UCSC Genome Browser.

Further reading

• Dell'Angelica EC, Ohno H, Ooi CE, et al. (1997). "AP-3: an adaptor-like protein complex with ubiquitous expression". EMBO J. 16 (5): 917–28. doi:10.1093/emboj/16.5.917. PMC 1169692. PMID 9118953.
• Dell'Angelica EC, Klumperman J, Stoorvogel W, Bonifacino JS (1998). "Association of the AP-3 adaptor complex with clathrin". Science. 280 (5362): 431–4. doi:10.1126/science.280.5362.431. PMID 9545220.
• Lim DS, Kirsch DG, Canman CE, et al. (1998). "ATM binds to beta-adaptin in cytoplasmic vesicles". Proc. Natl. Acad. Sci. U.S.A. 95 (17): 10146–51. doi:10.1073/pnas.95.17.10146. PMC 21476. PMID 9707615.
• Faundez VV, Kelly RB (2000). "The AP-3 complex required for endosomal synaptic vesicle biogenesis is associated with a casein kinase Ialpha-like isoform". Mol. Biol. Cell. 11 (8): 2591–604. doi:10.1091/mbc.11.8.2591. PMC 14942. PMID 10930456.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Dubois T, Zemlickova E, Howell S, Aitken A (2003). "Centaurin-alpha 1 associates in vitro and in vivo with nucleolin". Biochem. Biophys. Res. Commun. 301 (2): 502–8. doi:10.1016/S0006-291X(02)03010-3. PMID 12565890.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Chen C, Zou X, Ji C, et al. (2007). "Characterization of AP3B2_v2, a novel splice variant of human AP3B2". DNA Seq. 18 (3): 165–8. doi:10.1080/10425170600842121. PMID 17453999.