COPG2

Coatomer subunit gamma-2 is a protein that in humans is encoded by the COPG2 gene.[5][6][7]

COPG2
Identifiers
AliasesCOPG2, 2-COP, gamma-2-COP, coatomer protein complex subunit gamma 2, COPI coat complex subunit gamma 2
External IDsOMIM: 604355 MGI: 1858683 HomoloGene: 56292 GeneCards: COPG2
Gene location (Human)
Chr.Chromosome 7 (human)[1]
Band7q32.2Start130,506,238 bp[1]
End130,668,748 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

26958

54160

Ensembl

ENSG00000158623

ENSMUSG00000025607

UniProt

Q9UBF2

Q9QXK3

RefSeq (mRNA)

NM_012133
NM_001290033

NM_017478

RefSeq (protein)

NP_001276962
NP_036265

NP_059506

Location (UCSC)Chr 7: 130.51 – 130.67 MbChr 6: 30.75 – 30.9 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Interactions

COPG2 has been shown to interact with Dopamine receptor D1[8] and COPB1.[9][10]

References

  1. GRCh38: Ensembl release 89: ENSG00000158623 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000025607 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Blagitko N, Schulz U, Schinzel AA, Ropers HH, Kalscheuer VM (Jan 2000). "gamma2-COP, a novel imprinted gene on chromosome 7q32, defines a new imprinting cluster in the human genome". Hum Mol Genet. 8 (13): 2387–96. doi:10.1093/hmg/8.13.2387. PMID 10556286.
  6. Yamasaki K, Hayashida S, Miura K, Masuzaki H, Ishimaru T, Niikawa N, Kishino T (Nov 2000). "The novel gene, gamma2-COP (COPG2), in the 7q32 imprinted domain escapes genomic imprinting". Genomics. 68 (3): 330–5. doi:10.1006/geno.2000.6265. PMID 10995575.
  7. "Entrez Gene: COPG2 coatomer protein complex, subunit gamma 2".
  8. Bermak JC, Li M, Bullock C, Weingarten P, Zhou QY (Feb 2002). "Interaction of gamma-COP with a transport motif in the D1 receptor C-terminus". Eur. J. Cell Biol. 81 (2): 77–85. doi:10.1078/0171-9335-00222. PMID 11893085.
  9. Takatsu H, Futatsumori M, Yoshino K, Yoshida Y, Shin HW, Nakayama K (Jun 2001). "Similar subunit interactions contribute to assembly of clathrin adaptor complexes and COPI complex: analysis using yeast three-hybrid system". Biochem. Biophys. Res. Commun. 284 (4): 1083–9. doi:10.1006/bbrc.2001.5081. PMID 11409905.
  10. Futatsumori M, Kasai K, Takatsu H, Shin HW, Nakayama K (2000). "Identification and characterization of novel isoforms of COP I subunits". J Biochem. 128 (5): 793–801. doi:10.1093/oxfordjournals.jbchem.a022817. PMID 11056392.

Further reading


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