Corydaline

Corydaline is an acetylcholinesterase inhibitor isolated from Corydalis yanhusuo.[1]

Corydaline

Names
IUPAC name (13S,13aR)-2,3,9,10-Tetramethoxy-13-methyl-6,8,13,13a-tetrahydro-5H-isoquinolino[2,1-b]isoquinoline
Identifiers
CAS Number	518-69-4^Y
3D model (JSmol)	Interactive image Interactive image
ChemSpider	91533
PubChem CID	101301
UNII	08N392L8VX^Y
CompTox Dashboard (EPA)	DTXSID90199735
InChI InChI=1S/C22H27NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-11,13,21H,8-9,12H2,1-5H3/t13-,21+/m0/s1 Key: VRSRXLJTYQVOHC-YEJXKQKISA-N InChI=1/C22H27NO4/c1-13-15-6-7-18(24-2)22(27-5)17(15)12-23-9-8-14-10-19(25-3)20(26-4)11-16(14)21(13)23/h6-7,10-11,13,21H,8-9,12H2,1-5H3/t13-,21+/m0/s1 Key: VRSRXLJTYQVOHC-YEJXKQKIBZ
SMILES C[C@@H]1[C@@H]2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)OC)OC C[C@@H]1[C@@H]2C3=CC(=C(C=C3CCN2CC4=C1C=CC(=C4OC)OC)OC)OC
Properties
Chemical formula	C22H27NO4
Molar mass	369.461 g·mol^−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

References

1. Xiao, Hai-Tao; Peng, Jiao; Liang, Yan; Yang, Jie; Bai, Xue; Hao, Xiao-Yan; Yang, Fu-Mei; Sun, Qian-Yun (September 2011). "Acetylcholinesterase inhibitors from Corydalis yanhusuo". Natural Product Research. Taylor and Francis. 25 (15): 1418–1422. doi:10.1080/14786410802496911. ISSN 1478-6419. PMID 20234973.