CUMYL-THPINACA

CUMYL-THPINACA (also known as SGT-42) is an indazole-3-carboxamide based synthetic cannabinoid.[1] CUMYL-THPINACA acts as a potent agonist for the cannabinoid receptors, with approximately 6x selectivity for CB₁, having an EC₅₀ of 0.1nM for human CB₁ receptors and 0.59nM for human CB₂ receptors.[2]

CUMYL-THPINACA

Legal status
Legal status	CA: Schedule II DE: NpSG (Industrial and scientific use only) UK: Under Psychoactive Substances Act Illegal in China and Sweden
Identifiers
IUPAC name 1-(oxan-4-ylmethyl)-N-(2-phenylpropan-2-yl)indazole-3-carboxamide
CAS Number	1400742-50-8
PubChem CID	86273679
ChemSpider	48057932
Chemical and physical data
Formula	C23H27N3O2
Molar mass	377.488 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C(NC(C)(C)C1=CC=CC=C1)C2=NN(CC3CCOCC3)C4=C2C=CC=C4
InChI InChI=1S/C23H27N3O2/c1-23(2,18-8-4-3-5-9-18)24-22(27)21-19-10-6-7-11-20(19)26(25-21)16-17-12-14-28-15-13-17/h3-11,17H,12-16H2,1-2H3,(H,24,27) Key:HINCNLQQLQFMRD-UHFFFAOYSA-N

Legal status

Sweden's public health agency suggested to classify CUMYL-THPINACA as hazardous substance on November 10, 2014.[3]

As of October 2015 CUMYL-THPINACA is a controlled substance in China.[4]

See also

• 5F-CUMYL-PINACA
• 5F-SDB-006
• ADAMANTYL-THPINACA
• CUMYL-4CN-BINACA
• CUMYL-CBMINACA
• CUMYL-PICA
• CUMYL-PINACA
• SDB-006
• NNE1

References

1. "CUMYL-THPINACA". Cayman Chemical. Retrieved 11 July 2015.
2. Bowden; et al. (11 April 2013). "Patent WO 2014167530 - Cannabinoid compounds". New Zealand Patent application 623626. Retrieved 11 July 2015.
3. "Cannabinoider föreslås bli klassade som hälsofarlig vara". Retrieved 11 July 2015.
4. "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.