(Pyruvate, phosphate dikinase)-phosphate phosphotransferase

(Pyruvate, phosphate dikinase)-phosphate phosphotransferase (EC 2.7.4.27, PPDK regulatory protein, pyruvate, phosphate dikinase regulatory protein, bifunctional dikinase regulatory protein, PDRP1 (gene)) is an enzyme with systematic name (pyruvate, phosphate dikinase) phosphate:phosphate phosphotransferase.[1][2][3][4][5] This enzyme catalyses the following chemical reaction

[pyruvate, phosphate dikinase] phosphate + phosphate [pyruvate, phosphate dikinase] + diphosphate
(Pyruvate, phosphate dikinase)-phosphate phosphotransferase
Identifiers
EC number2.7.4.27
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

The enzyme from the plants maize and arabidopsis is bifunctional and also catalyses the phosphorylation of pyruvate (EC 2.7.11.32).

References
  1. Burnell JN, Hatch MD (May 1984). "Regulation of C4 photosynthesis: identification of a catalytically important histidine residue and its role in the regulation of pyruvate,Pi dikinase". Archives of Biochemistry and Biophysics. 231 (1): 175–82. doi:10.1016/0003-9861(84)90375-8. PMID 6326674.
  2. Burnell JN, Hatch MD (March 1985). "Regulation of C4 photosynthesis: purification and properties of the protein catalyzing ADP-mediated inactivation and Pi-mediated activation of pyruvate,Pi dikinase". Archives of Biochemistry and Biophysics. 237 (2): 490–503. doi:10.1016/0003-9861(85)90302-9. PMID 2983615.
  3. Chastain CJ, Botschner M, Harrington GE, Thompson BJ, Mills SE, Sarath G, Chollet R (March 2000). "Further analysis of maize C(4) pyruvate,orthophosphate dikinase phosphorylation by its bifunctional regulatory protein using selective substitutions of the regulatory Thr-456 and catalytic His-458 residues". Archives of Biochemistry and Biophysics. 375 (1): 165–70. doi:10.1006/abbi.1999.1651. PMID 10683263.
  4. Burnell JN, Chastain CJ (June 2006). "Cloning and expression of maize-leaf pyruvate, Pi dikinase regulatory protein gene". Biochemical and Biophysical Research Communications. 345 (2): 675–80. doi:10.1016/j.bbrc.2006.04.150. PMID 16696949.
  5. Chastain CJ, Xu W, Parsley K, Sarath G, Hibberd JM, Chollet R (March 2008). "The pyruvate, orthophosphate dikinase regulatory proteins of Arabidopsis possess a novel, unprecedented Ser/Thr protein kinase primary structure". The Plant Journal. 53 (5): 854–63. doi:10.1111/j.1365-313x.2007.03366.x. PMID 17996018.
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