FCGR3A

Low affinity immunoglobulin gamma Fc region receptor III-A is a protein that in humans is encoded by the FCGR3A gene.[5][6] It is also known as CD16a as it is part of the cluster of differentiation cell surface molecules.

FCGR3A
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesFCGR3A, CD16, CD16A, FCG3, FCGR3, FCGRIII, FCR-10, FCRIII, FCRIIIA, IGFR3, IMD20, Fc fragment of IgG receptor IIIa
External IDsOMIM: 146740 MGI: 2179523 HomoloGene: 477 GeneCards: FCGR3A
Gene location (Human)
Chr.Chromosome 1 (human)[1]
Band1q23.3Start161,541,759 bp[1]
End161,550,737 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

2214

246256

Ensembl

ENSG00000203747

ENSMUSG00000059089

UniProt

P08637

A0A0B4J1G0

RefSeq (mRNA)

NM_144559

RefSeq (protein)

NP_653142

Location (UCSC)Chr 1: 161.54 – 161.55 MbChr 1: 171.02 – 171.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

  1. GRCh38: Ensembl release 89: ENSG00000203747 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000059089 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. Qiu WQ, de Bruin D, Brownstein BH, Pearse R, Ravetch JV (May 1990). "Organization of the human and mouse low-affinity Fc gamma R genes: duplication and recombination". Science. 248 (4956): 732–5. doi:10.1126/science.2139735. PMID 2139735.
  6. "Entrez Gene: FCGR3A Fc fragment of IgG, low affinity IIIa, receptor (CD16a)".

Further reading

  • Overview of all the structural information available in the PDB for UniProt: P08637 (Low affinity immunoglobulin gamma Fc region receptor III-A) at the PDBe-KB.


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