PGRMC2

Progesterone receptor membrane component 2 (abbreviated PGRMC2) is a protein which is encoded by the PGRMC2 gene.[5][6] It has been detected in the placenta, liver, and spermatozoa, among other areas.[5][6]

PGRMC2
Identifiers
Aliases	PGRMC2, DG6, PMBP, progesterone receptor membrane component 2
External IDs	OMIM: 607735 MGI: 1918054 HomoloGene: 38169 GeneCards: PGRMC2
Gene location (Human) Chr. Chromosome 4 (human)[1] Band 4q28.2 Start 128,269,237 bp[1] End 128,288,829 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 B Start 41,066,326 bp[2] End 41,083,046 bp[2]
Gene ontology Molecular function • steroid hormone receptor activity • steroid binding • heme binding • lipid binding • GO:0001948 protein binding Cellular component • integral component of membrane • nuclear envelope • membrane Biological process • steroid hormone mediated signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	10424	70804
Ensembl	ENSG00000164040	ENSMUSG00000049940
UniProt	O15173	Q80UU9
RefSeq (mRNA)	NM_006320	NM_027558
RefSeq (protein)	NP_006311	NP_081834
Location (UCSC)	Chr 4: 128.27 – 128.29 Mb	Chr 3: 41.07 – 41.08 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

See also

• PGRMC
• PGRMC1
• Membrane progesterone receptor

References

1. GRCh38: Ensembl release 89: ENSG00000164040 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000049940 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Gerdes D, Wehling M, Leube B, Falkenstein E (1998). "Cloning and tissue expression of two putative steroid membrane receptors". Biol. Chem. 379 (7): 907–11. doi:10.1515/bchm.1998.379.7.907. PMID 9705155.
6. Lösel R, Breiter S, Seyfert M, Wehling M, Falkenstein E (2005). "Classic and non-classic progesterone receptors are both expressed in human spermatozoa". Horm. Metab. Res. 37 (1): 10–4. doi:10.1055/s-2005-861023. PMID 15702432.