Epigen
Epigen also known as epithelial mitogen is a protein that in humans is encoded by the EPGN gene.[5][6]
Function
The protein encoded by this gene is a member of the epidermal growth factor family. Members of this family are ligands for the epidermal growth factor receptor and play a role in cell survival, proliferation and migration. This protein has been reported to have high mitogenic activity but low affinity for its receptor. Expression of this transcript and protein have been reported in cancer specimens of the breast, bladder, and prostate.[5]
gollark: Sophonts are defined as nondeterministic in some way, right? Presumably you could, though, force them to make a particular decision by making it the only consistent one. Or does the universe just proactively not allow that kind of situation?
gollark: Vaguely relatedly, how do the self-consistency things interact with the universe's enforced free will?
gollark: The simplest self-consistent result of any form of time travel existing is that you just never use it ever.
gollark: Would it be convention to say "exactly one of the cats is sleeping" if you meant the English thing, then?
gollark: Quotes are `>`.
References
- GRCh38: Ensembl release 89: ENSG00000182585 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000035020 - Ensembl, May 2017
- "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- "Entrez Gene: Epithelial mitogen".
- Schneider MR, Yarden Y (2014). "Structure and function of epigen, the last EGFR ligand". Semin. Cell Dev. Biol. 28: 57–61. doi:10.1016/j.semcdb.2013.12.011. PMC 4037347. PMID 24374012.
External links
- epigen at the US National Library of Medicine Medical Subject Headings (MeSH)
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