Alacizumab pegol
Alacizumab pegol is an antineoplastic agent. Chemically, it is a pegylated F(ab')2 fragment of a monoclonal antibody.[1]
Monoclonal antibody | |
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Type | F(ab')2 fragment |
Source | Humanized (from mouse) |
Target | VEGFR2 |
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References
- International Nonproprietary Names for Pharmaceutical Substances (INN), World Health Organization.
Monoclonals for bone, musculoskeletal, circulatory, and neurologic systems | |||||||||
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Bone ("-os-", "-s(o)-") |
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Musculoskeletal ("-mul-") |
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Circulatory ("-c(i[r])-") |
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Neurologic ("-ne(u)(r)-") |
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Angiogenesis inhibitor ("-anibi-") |
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Growth factor ("-gr(o)-") |
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Angiopoietin |
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CNTF | |||||||||||
EGF (ErbB) |
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FGF |
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HGF (c-Met) |
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IGF |
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LNGF (p75NTR) |
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PDGF |
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RET (GFL) |
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SCF (c-Kit) | |||||||||||
TGFβ |
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Trk |
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VEGF |
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Others |
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