Cimoxatone

Cimoxatone (MD 780515) is a reversible inhibitor of MAO-A (RIMA).[1] It has a significant food interaction–related adverse effect in combination with tyramine.[2] It was never marketed.

Cimoxatone

Clinical data
ATC code	none
Identifiers
IUPAC name 3-[[4-[5-(methoxymethyl)-2-oxo-oxazolidin-3-yl]phenoxy]methyl]benzonitrile
CAS Number	73815-11-9^Y
PubChem CID	52542
ChemSpider	47493^Y
UNII	V6FT1QJ7VL
KEGG	D02581^Y
ChEMBL	ChEMBL2104092^N
ECHA InfoCard	100.070.537
Chemical and physical data
Formula	C19H18N2O4
Molar mass	338.363 g·mol^−1
InChI InChI=1S/C19H18N2O4/c1-23-13-18-11-21(19(22)25-18)16-5-7-17(8-6-16)24-12-15-4-2-3-14(9-15)10-20/h2-9,18H,11-13H2,1H3^Y Key:MVVJINIUPYKZHR-UHFFFAOYSA-N^Y
^NY (what is this?)  (verify)

See also

• Monoamine oxidase inhibitor

References

1. Nair NP, Ahmed SK, Kin NM, West TE (1995). "Reversible and selective inhibitors of monoamine oxidase A in the treatment of depressed elderly patients". Acta Psychiatr Scand Suppl. 386: 28–35. doi:10.1111/j.1600-0447.1995.tb05921.x. PMID 7717092.
2. Nair NP, Ahmed SK, Kin NM (November 1993). "Biochemistry and pharmacology of reversible inhibitors of MAO-A agents: focus on moclobemide". J Psychiatry Neurosci. 18 (5): 214–25. PMC 1188542. PMID 7905288.