Lithium citrate

Lithium citrate (Li₃C₆H₅O₇) is a chemical compound of lithium and citrate that is used as a mood stabilizer in psychiatric treatment of manic states and bipolar disorder.[1][2] There is extensive pharmacology of lithium, the active component of this salt.

Lithium citrate

Names
Other names Trilithium citrate trilithium 2-hydroxypropane-1,2,3-tricarboxylate
Identifiers
CAS Number	919-16-4^Y
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1201170^N
ChemSpider	12932^Y
ECHA InfoCard	100.011.860
PubChem CID	13520
RTECS number	TZ8616000
UNII	3655633623^Y
CompTox Dashboard (EPA)	DTXSID70883185
InChI InChI=1S/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3^Y Key: WJSIUCDMWSDDCE-UHFFFAOYSA-K^Y InChI=1/C6H8O7.3Li/c7-3(8)1-6(13,5(11)12)2-4(9)10;;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;;/q;3*+1/p-3 Key: WJSIUCDMWSDDCE-DFZHHIFOAV
SMILES [Li+].[Li+].[Li+].O=C([O-])CC(O)(C([O-])=O)CC(=O)[O-]
Properties
Chemical formula	Li3C6H5O7
Molar mass	209.923 g mol^−1
Appearance	Odorless white powder
Melting point	decomposes at 105 °C (221 °F; 378 K)
Hazards
Main hazards	Toxic
R-phrases (outdated)	R22 R36 R37 R38
Flash point	N/A
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

Lithia water contains various lithium salts, including the citrate. An early version of Coca-Cola available in pharmacies' soda fountains called Lithia Coke was a mixture of Coca-Cola syrup and lithia water. The soft drink 7Up was originally named "Bib-Label Lithiated Lemon-Lime Soda" when it was formulated in 1929 because it contained lithium citrate. The beverage was a patent medicine marketed as a cure for hangover. Lithium citrate was removed from 7Up in 1948.[3]

References

1. Medication description
2. Medical use Archived 2006-06-15 at the Wayback Machine
3. Gielen, Marcel; Edward R. T. Tiekink (2005). Metallotherapeutic drugs and metal-based diagnostic agents: The use of metals in medicine. John Wiley and Sons. p. 3. ISBN 0-470-86403-6.