Alkylglycerone phosphate synthase
Alkylglycerone phosphate synthase (EC 2.5.1.26, alkyldihydroxyacetonephosphate synthase, alkyldihydroxyacetone phosphate synthetase, alkyl DHAP synthetase, alkyl-DHAP, dihydroxyacetone-phosphate acyltransferase, DHAP-AT) is an enzyme associated with Type 3 Rhizomelic chondrodysplasia punctata.[1][2] This enzyme catalyses the following chemical reaction
- 1-acyl-glycerone 3-phosphate + a long-chain alcohol an alkyl-glycerone 3-phosphate + a long-chain acid anion
| alkylglycerone-phosphate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.26 | ||||||||
| CAS number | 64060-42-0 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
| alkylglycerone phosphate synthase | |
|---|---|
| Identifiers | |
| Symbol | AGPS |
| NCBI gene | 8540 |
| HGNC | 327 |
| OMIM | 603051 |
| RefSeq | NM_003659 |
| UniProt | O00116 |
| Other data | |
| EC number | 2.5.1.26 |
| Locus | Chr. 2 q31 |
References
- Brown AJ, Snyder F (August 1982). "Alkyldihydroxyacetone-P synthase. Solubilization, partial purification, new assay method, and evidence for a ping-pong mechanism". The Journal of Biological Chemistry. 257 (15): 8835–9. PMID 7096336.
- Wykle RL, Plantadosi C, Snyder F (May 1972). "The role of acyldihydroxyacetone phosphate, reduced nicotinamide adenine dinucleotide, and reduced nicotinamide adenine dinucleotide phosphate in the biosynthesis of O-alkyl glycerolipids by microsomal enzymes of Ehrlich ascites tumor". The Journal of Biological Chemistry. 247 (9): 2944–8. PMID 4401994.
External links
- Alkylglycerone-phosphate+synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.