Norpipanone

Norpipanone (INN, BAN; Hexalgon) is an opioid analgesic related to methadone which was developed in Germany and distributed in Hungary, Argentina, and other countries.[1][2] It had originally not been under international control but upon observation of case reports of addiction it was reviewed and shortly thereafter became a controlled substance.[1][2] In the United States, it is a Schedule I controlled substance (ACSCN 9636, zero annual manufacturing quota as of 2014). The salts in use are the hydrobromide (free base conversion ratio 0.806) and hydrochloride (0.902).

Norpipanone
Clinical data
Other namesHerchst 10495, NIH-7557
ATC code
  • None
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
CompTox Dashboard (EPA)
ECHA InfoCard100.008.383
Chemical and physical data
FormulaC23H29NO
Molar mass335.491 g·mol−1
3D model (JSmol)

Synthesis

Norpipanone synthesis:[3][4]
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gollark: Sooooo... is there a stable similar one?
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gollark: .........
gollark: I want to rewrite potatOS in such a great language.

See also

References

  1. John B Buckingham (December 1995). Dictionary of Organic Compounds. CRC Press. p. 2883. ISBN 978-0-412-54090-5. Retrieved 11 May 2012.
  2. David S. Patterson (12 March 2002). Foreign Relations of the United States, 1961-1963, Volume XXV: Organization of Foreign Policy; Information Policy; United Nations; Scientific Matters. Government Printing Office. pp. 766–767. ISBN 978-0-16-050885-1. Retrieved 11 May 2012.
  3. Duprè, D. J.; Elks, J.; Hems, B. A.; Speyer, K. N.; Evans, R. M. (1949). "113. Analgesics. Part I. Esters and ketones derived from α-amino-ω-cyano-ωωdiarylalkanes". Journal of the Chemical Society (Resumed). Chemical Society: 500. doi:10.1039/JR9490000500.
  4. Bockmühl, M.; Ehrhart, G. (1949). "Über eine neue Klasse von spasmolytisch und analgetisch wirkenden Verbindungen, I". Justus Liebigs Annalen der Chemie. 561: 52. doi:10.1002/jlac.19495610107.



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