NCAPD3

Condensin-2 complex subunit D3 (CAP-D3) also known as non-SMC condensin II complex subunit D3 (NCAPD3) is a protein that in humans is encoded by the NCAPD3 gene.[5][6][7][8] CAP-D3 is a subunit of condensin II, a large protein complex involved in chromosome condensation.

NCAPD3
Identifiers
Aliases	NCAPD3, CAP-D3, CAPD3, hCAP-D3, hHCP-6, hcp-6, non-SMC condensin II complex subunit D3, MCPH22
External IDs	OMIM: 609276 MGI: 2142989 HomoloGene: 41021 GeneCards: NCAPD3
Gene location (Human) Chr. Chromosome 11 (human)[1] Band 11q25 Start 134,150,119 bp[1] End 134,225,454 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 A4 Start 27,030,175 bp[2] End 27,095,315 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • methylated histone binding • chromatin binding • GO:0001948 protein binding • histone binding Cellular component • membrane • cell nucleus • nuclear condensin complex • nuclear pericentric heterochromatin • condensed chromosome, centromeric region • nucleoplasm Biological process • mitotic chromosome condensation • chromosome separation • cell division • cell cycle • chromosome condensation • meiotic chromosome condensation Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23310	78658
Ensembl	ENSG00000151503	ENSMUSG00000035024
UniProt	P42695	Q6ZQK0
RefSeq (mRNA)	NM_015261 NM_001372065 NM_001372068 NM_001372069 NM_001372070	NM_178113 NM_001382847
RefSeq (protein)	NP_056076 NP_001358994 NP_001358997 NP_001358998 NP_001358999	NP_835214 NP_001369776
Location (UCSC)	Chr 11: 134.15 – 134.23 Mb	Chr 9: 27.03 – 27.1 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000151503 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000035024 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Nomura N, Nagase T, Miyajima N, Sazuka T, Tanaka A, Sato S, Seki N, Kawarabayasi Y, Ishikawa K, Tabata S (December 1995). "Prediction of the coding sequences of unidentified human genes. II. The coding sequences of 40 new genes (KIAA0041-KIAA0080) deduced by analysis of cDNA clones from human cell line KG-1". DNA Research. 1 (5): 223–229. doi:10.1093/dnares/1.5.223. PMID 7584044.
6. Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA (June 1996). "A "double adaptor" method for improved shotgun library construction". Analytical Biochemistry. 236 (1): 107–113. doi:10.1006/abio.1996.0138. PMID 8619474.
7. Ono T, Losada A, Hirano M, Myers MP, Neuwald AF, Hirano T (October 2003). "Differential contributions of condensin I and condensin II to mitotic chromosome architecture in vertebrate cells". Cell. 115 (1): 109–121. doi:10.1016/S0092-8674(03)00724-4. PMID 14532007.
8. "NCAPD3 non-SMC condensin II complex, subunit D3". National Center for Biotechnology Information. Retrieved June 10, 2012.

Further reading

• Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Andersen JS, Lam YW, Leung AK, et al. (2005). "Nucleolar proteome dynamics". Nature. 433 (7021): 77–83. Bibcode:2005Natur.433...77A. doi:10.1038/nature03207. PMID 15635413.
• Nousiainen M, Silljé HH, Sauer G, et al. (2006). "Phosphoproteome analysis of the human mitotic spindle". Proc. Natl. Acad. Sci. U.S.A. 103 (14): 5391–6. Bibcode:2006PNAS..103.5391N. doi:10.1073/pnas.0507066103. PMC 1459365. PMID 16565220.