Endoproteinase Lys-C

Endoproteinase Lys-C is a protease that cleaves proteins on the C-terminal side of lysine residues. This enzyme is naturally found in the bacterium Lysobacter enzymogenes and is commonly used in protein sequencing.[1][2] Lys-C activity is optimal in the pH range 7.0 - 9.0.[3]

See also

References
  1. Jekel, PA; Weijer, WJ; Beintema, JJ (15 October 1983). "Use of endoproteinase Lys-C from Lysobacter enzymogenes in protein sequence analysis". Analytical Biochemistry. 134 (2): 347–54. doi:10.1016/0003-2697(83)90308-1. PMID 6359954.
  2. Shah, Haroun N.; Gharbia, Saheer E. (2010). Mass Spectrometry for Microbial Proteomics. Chichester, UK: Wiley. p. 136.
  3. http://www.promega.com/catalog/catalogproducts.aspx?categoryname=productleaf_2202


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