OR6C3

Olfactory receptor 6C3 is a protein that in humans is encoded by the OR6C3 gene.[4]

OR6C3
Identifiers
Aliases	OR6C3, OST709, olfactory receptor family 6 subfamily C member 3
External IDs	MGI: 3030637 HomoloGene: 105153 GeneCards: OR6C3
Gene location (Human) Chr. Chromosome 12 (human)[1] Band 12q13.2 Start 55,330,043 bp[1] End 55,332,687 bp[1]
Gene ontology Molecular function • signal transducer activity • G-protein coupled receptor activity • olfactory receptor activity Cellular component • cell membrane • membrane • integral component of membrane Biological process • signal transduction • response to stimulus • sensory perception of smell • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	254786	258547
Ensembl	ENSG00000205329	n/a
UniProt	Q9NZP0	Q8VFI3
RefSeq (mRNA)	NM_054104	NM_146554
RefSeq (protein)	NP_473445	NP_666765
Location (UCSC)	Chr 12: 55.33 – 55.33 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000205329 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR6C3 olfactory receptor, family 6, subfamily C, member 3".

Further reading

• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
• Scherer SE, Muzny DM, Buhay CJ, et al. (2006). "The finished DNA sequence of human chromosome 12". Nature. 440 (7082): 346–51. doi:10.1038/nature04569. PMID 16541075.

External links

• OR6C3+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.