OR2T2

Olfactory receptor 2T2 is a protein that in humans is encoded by the OR2T2 gene.[3][4]

OR2T2
Identifiers
Aliases	OR2T2, OR1-43, OR2T2P, olfactory receptor family 2 subfamily T member 2
External IDs	HomoloGene: 66506 GeneCards: OR2T2
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q44 Start 248,445,512 bp[1] End 248,455,725 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	401992	n/a
Ensembl	ENSG00000275754 ENSG00000196240 ENSG00000276821	n/a
UniProt	Q6IF00	n/a
RefSeq (mRNA)	NM_001004136	n/a
RefSeq (protein)	NP_001004136	n/a
Location (UCSC)	Chr 1: 248.45 – 248.46 Mb	n/a
PubMed search	[2]	n/a
Wikidata
View/Edit Human

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. ENSG00000196240, ENSG00000276821 GRCh38: Ensembl release 89: ENSG00000275754, ENSG00000196240, ENSG00000276821 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. Malnic B, Godfrey PA, Buck LB (Feb 2004). "The human olfactory receptor gene family". Proc Natl Acad Sci U S A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
4. "Entrez Gene: OR2T2 olfactory receptor, family 2, subfamily T, member 2".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.

External links

• OR2T2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.