OR6B2

Olfactory receptor 6B2 is a protein that in humans is encoded by the OR6B2 gene.[4]

OR6B2
Identifiers
Aliases	OR6B2, OR2-1, OR6B2P, olfactory receptor family 6 subfamily B member 2
External IDs	MGI: 3031250 HomoloGene: 17472 GeneCards: OR6B2
Gene location (Human) Chr. Chromosome 2 (human)[1] Band 2q37.3 Start 240,028,965 bp[1] End 240,030,456 bp[1]
Gene ontology Molecular function • G-protein coupled receptor activity • odorant binding • olfactory receptor activity • signal transducer activity Cellular component • integral component of membrane • cell membrane • membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	389090	259040
Ensembl	ENSG00000182083	n/a
UniProt	Q6IFH4	Q8VGU4
RefSeq (mRNA)	NM_001005853	NM_147038
RefSeq (protein)	NP_001005853	NP_667249
Location (UCSC)	Chr 2: 240.03 – 240.03 Mb	n/a
PubMed search	[2]	[3]
Wikidata
View/Edit Human View/Edit Mouse

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[4]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000182083 - Ensembl, May 2017
2. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
3. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Entrez Gene: OR6B2 olfactory receptor, family 6, subfamily B, member 2".

Further reading

• Malnic B, Godfrey PA, Buck LB (February 2004). "The human olfactory receptor gene family". Proceedings of the National Academy of Sciences of the United States of America. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR6B2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.