OR1L6

Olfactory receptor 1L6 is a protein that in humans is encoded by the OR1L6 gene.[5]

OR1L6
Identifiers
Aliases	OR1L6, HG16, OR1L7, OR9-30, OR1K1, olfactory receptor family 1 subfamily L member 6
External IDs	MGI: 3030199 HomoloGene: 74156 GeneCards: OR1L6
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9q33.2 Start 122,742,303 bp[1] End 122,750,783 bp[1]
Gene location (Mouse) Chr. Chromosome 2 (mouse)[2] Band 2|2 B Start 37,188,198 bp[2] End 37,206,019 bp[2]
Gene ontology Molecular function • signal transducer activity • G-protein coupled receptor activity • olfactory receptor activity Cellular component • cell membrane • membrane • integral component of membrane Biological process • sensory perception of smell • signal transduction • detection of chemical stimulus involved in sensory perception of smell • response to stimulus • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	392390	258656
Ensembl	ENSG00000171459	ENSMUSG00000059429
UniProt	Q8NGR2	Q8VFT2
RefSeq (mRNA)	NM_001004453	NM_146662
RefSeq (protein)	NP_001004453	NP_666873
Location (UCSC)	Chr 9: 122.74 – 122.75 Mb	Chr 2: 37.19 – 37.21 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000171459 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000059429 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR1L6 olfactory receptor, family 1, subfamily L, member 6".

Further reading

• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR1L6+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.