OR2S2

Olfactory receptor 2S2 is a protein that in humans is encoded by the OR2S2 gene.[5]

OR2S2
Identifiers
Aliases	OR2S2, OR37A, OST715, olfactory receptor family 2 subfamily S member 2 (gene/pseudogene), olfactory receptor family 2 subfamily S member 2
External IDs	MGI: 1352681 HomoloGene: 84331 GeneCards: OR2S2
Gene location (Human) Chr. Chromosome 9 (human)[1] Band 9p13.3 Start 35,957,108 bp[1] End 35,958,154 bp[1]
Gene location (Mouse) Chr. Chromosome 4 (mouse)[2] Band 4|4 B1 Start 43,851,565 bp[2] End 43,857,595 bp[2]
RNA expression pattern More reference expression data
Gene ontology Molecular function • signal transducer activity • olfactory receptor activity • G-protein coupled receptor activity Cellular component • cell membrane • membrane • integral component of membrane Biological process • sensory perception of smell • signal transduction • response to stimulus • detection of chemical stimulus involved in sensory perception of smell • G-protein coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	56656	29845
Ensembl	ENSG00000278889	ENSMUSG00000071000
UniProt	Q9NQN1	Q9QZ22
RefSeq (mRNA)	NM_019897	NM_019473
RefSeq (protein)	NP_063950	NP_062346
Location (UCSC)	Chr 9: 35.96 – 35.96 Mb	Chr 4: 43.85 – 43.86 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

• Olfactory receptor

References

1. GRCh38: Ensembl release 89: ENSG00000278889 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000071000 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. "Entrez Gene: OR2S2 olfactory receptor, family 2, subfamily S, member 2".

Further reading

• Strotmann J, Hoppe R, Conzelmann S, et al. (1999). "Small subfamily of olfactory receptor genes: structural features, expression pattern and genomic organization". Gene. 236 (2): 281–91. doi:10.1016/S0378-1119(99)00275-9. PMID 10452948.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. CiteSeerX 10.1.1.145.6233. doi:10.1006/geno.2002.6830. PMID 12213199.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Hoppe R, Breer H, Strotmann J (2004). "Organization and evolutionary relatedness of OR37 olfactory receptor genes in mouse and human". Genomics. 82 (3): 355–64. doi:10.1016/S0888-7543(03)00116-2. PMID 12906860.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.
• Humphray SJ, Oliver K, Hunt AR, et al. (2004). "DNA sequence and analysis of human chromosome 9". Nature. 429 (6990): 369–74. doi:10.1038/nature02465. PMC 2734081. PMID 15164053.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

External links

• OR2S2+protein,+human at the US National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.