Non-noradrenergic, non-cholinergic transmitter

A non-noradrenergic, non-cholinergic transmitter (NANC) is a neurotransmitter of the autonomic nervous system (ANS) that is neither acetylcholine, norepinephrine, nor epinephrine.

Comparison table

This table compares different NANCs in the PNS:

Neurotransmitter Type Location[1] Function[1]
ATP non-peptide postganglionic sympathetic neurons (e.g. in blood vessels & vas deferens) Fast depolarization/contraction (vasoconstriction)
GABA non-peptide ENSs peristalsis
5-HT non-peptide ENSs peristalsis
dopamine non-peptide some SNSs (e.g. kidney) vasodilation
NO non-peptide gastric nerves & Pelvic Nerve
NPY peptide postganglionic sympathetic neurons (e.g. blood vessels)
  • enhance vasoconstrictor action of noradrenaline
  • noradrenaline release inhibitor
VIP peptide
  • parasympathetic nerves to salivary glands
  • NANC innervation to smooth muscle of airways
  • parasympathetic ganglia in sphincters, gallbladder and small intestine
GnRH peptide sympathetic ganglia
  • slow depolarization
  • acetylcholine cotransmitter
substance P peptide
  • sympathetic ganglia
  • ENSs
  • slow depolarization
  • acetylcholine cotransmitter
CGRP peptide non-myelinated sensory neurons
gollark: Because they're simpler?
gollark: muahahaha
gollark: ++delete school
gollark: I'm ponderinating, now, what™ commands this system needs.
gollark: EWO hosting, why?

References
  1. Unless else specified in table, then ref is: Rang, H. P. (2003). Pharmacology. Edinburgh: Churchill Livingstone. ISBN 0-443-07145-4. Page 132


This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.