Percavirus

Percavirus is a genus of viruses in the order Herpesvirales, in the family Herpesviridae, in the subfamily Gammaherpesvirinae. Mammals serve as natural hosts. There are currently six species in this genus including the type species Equid gammaherpesvirus 2. Diseases associated with this genus include: conjunctivitis, immunosuppression in foals, pneumonia, respiratory disease.[1][2]

Percavirus
Virus classification
(unranked): Virus
Realm: Duplodnaviria
Kingdom: Heunggongvirae
Phylum: Peploviricota
Class: Herviviricetes
Order: Herpesvirales
Family: Herpesviridae
Subfamily: Gammaherpesvirinae
Genus: Percavirus
Type species
Equid gammaherpesvirus 2
Species

See text

Species

The genus consists of the following six species:[2]

Structure

Viruses in Percavirus are enveloped, with icosahedral, spherical to pleomorphic, and round geometries, and T=16 symmetry. The diameter is around 150-200 nm. Genomes are linear and non-segmented, around 180kb in length.[1]

GenusStructureSymmetryCapsidGenomic arrangementGenomic segmentation
PercavirusSpherical pleomorphicT=16EnvelopedLinearMonopartite

Life cycle

Viral replication is nuclear, and is lysogenic. Entry into the host cell is achieved by attachment of the viral glycoproteins to host receptors, which mediates endocytosis. Replication follows the dsDNA bidirectional replication model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and budding. Mammals serve as the natural host.[1]

GenusHost detailsTissue tropismEntry detailsRelease detailsReplication siteAssembly siteTransmission
PercavirusMammalsB-lymphocytesGlycoprotiensBuddingNucleusNucleusSex; saliva
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References
  1. "Viral Zone". ExPASy. Retrieved 15 June 2015.
  2. "Virus Taxonomy: 2019 Release". talk.ictvonline.org. International Committee on Taxonomy of Viruses. Retrieved 9 May 2020.
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