Lasalocid

Lasalocid is an antibacterial agent and a coccidiostat, which is produced by strains of Streptomyces lasaliensis. It is the drug in the feed additives called Bovatec and Avatec.[1]

Lasalocid

Clinical data
AHFS/Drugs.com	International Drug Names
ATCvet code	QP51AH02 (WHO)
Identifiers
IUPAC name 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-
CAS Number	25999-31-9^N
PubChem CID	5360807
ChemSpider	4514598^Y
UNII	W7V2ZZ2FWB
KEGG	D04671^Y
ChEMBL	ChEMBL145347^Y
CompTox Dashboard (EPA)	DTXSID9048485
ECHA InfoCard	100.043.077
Chemical and physical data
Formula	C34H54O8
Molar mass	590.798 g·mol^−1
3D model (JSmol)	Interactive image
SMILES O=C(O)c1c(O)c(ccc1CC[C@@H](C)[C@H](O)[C@@H](C(=O)[C@@H]([C@H]3O[C@@]([C@@H]2O[C@H]([C@](O)(CC2)CC)C)(CC)C[C@@H]3C)CC)C)C
InChI InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1^Y Key:BBMULGJBVDDDNI-OWKLGTHSSA-N^Y
^NY (what is this?)  (verify)

Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can also transport big organic cations like dopamine.

Horses and dogs[2] are very susceptible to the toxic effects of lasalocid, and it should never be administered to non-target species.

References

1. FOIA Drug Summaries.
2. BMJ Veterinary Record