Isoflavone-7-O-beta-glucoside 6"-O-malonyltransferase
In enzymology, an isoflavone-7-O-beta-glucoside 6"-O-malonyltransferase (EC 2.3.1.115) is an enzyme that catalyzes the chemical reaction
- malonyl-CoA + biochanin A 7-O-beta-D-glucoside CoA + biochanin A 7-O-(6-O-malonyl-beta-D-glucoside)
| isoflavone-7-O-beta-glucoside 6-O-malonyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.3.1.115 | ||||||||
| CAS number | 93585-97-8 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are malonyl-CoA and biochanin A 7-O-beta-D-glucoside, whereas its two products are CoA and biochanin A 7-O-(6-O-malonyl-beta-D-glucoside).
This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is malonyl-CoA:isoflavone-7-O-beta-D-glucoside 6"-O-malonyltransferase. Other names in common use include flavone/flavonol 7-O-beta-D-glucoside malonyltransferase, flavone (flavonol) 7-O-glycoside malonyltransferase, malonyl-CoA:flavone/flavonol 7-O-glucoside malonyltransferase, MAT-7, malonyl-coenzyme A:isoflavone 7-O-glucoside-6"-malonyltransferase, and malonyl-coenzyme A:flavone/flavonol-7-O-glycoside malonyltransferase. This enzyme participates in flavonoid biosynthesis and isoflavonoid biosynthesis.
References
- Koester J, Bussmann R, Barz W (1984). "Malonyl-coenzyme A:isoflavone 7-O-glucoside-6"-O-malonyltransferase from roots of chick pea (Cicer arietinum L.)". Arch. Biochem. Biophys. 234 (2): 513–21. doi:10.1016/0003-9861(84)90298-4. PMID 6497385.
- Matern U, Feser C, Hammer D (1983). "Further characterization and regulation of malonyl-coenzyme A: flavonoid glucoside malonyltransferases from parsley cell suspension cultures". Arch. Biochem. Biophys. 226 (1): 206–17. doi:10.1016/0003-9861(83)90286-2. PMID 6639051.