IL17RD

Interleukin 17 receptor D is a protein that in humans is encoded by the IL17RD gene. [5]

IL17RD
Identifiers
AliasesIL17RD, HH18, IL-17RD, IL17RLM, SEF, interleukin 17 receptor D
External IDsOMIM: 606807 MGI: 2159727 HomoloGene: 9717 GeneCards: IL17RD
Gene location (Human)
Chr.Chromosome 3 (human)[1]
Band3p14.3Start57,089,982 bp[1]
End57,170,306 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

54756

171463

Ensembl

ENSG00000144730

ENSMUSG00000040717

UniProt

Q8NFM7

Q8JZL1

RefSeq (mRNA)

NM_017563
NM_001318864

NM_027265
NM_134437

RefSeq (protein)

NP_001305793
NP_060033

NP_602319

Location (UCSC)Chr 3: 57.09 – 57.17 MbChr 14: 27.04 – 27.11 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

This gene encodes a membrane protein belonging to the interleukin-17 receptor (IL-17R) protein family. The encoded protein is a component of the interleukin-17 receptor signaling complex, and the interaction between this protein and IL-17R does not require the interleukin. The gene product also affects fibroblast growth factor signaling, inhibiting or stimulating growth through MAPK/ERK signaling. Alternate splicing generates multiple transcript variants encoding distinct isoforms.

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References
  1. GRCh38: Ensembl release 89: ENSG00000144730 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000040717 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: Interleukin 17 receptor D". Retrieved 2016-04-17.

Further reading


This article incorporates text from the United States National Library of Medicine, which is in the public domain.

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