HLA-B55
HLA-B55 (B55) is an HLA-B serotype. B55 is a split antigen from the B22 broad antigen, sister serotypes are B54 and B56. The serotype identifies the more common HLA-B*55 gene products.[1] (For terminology help see: HLA-serotype tutorial)
major histocompatibility complex (human), class I, B55 | ||
| Alleles | B*5501, B*5502 | |
| Structure (See HLA-B) | ||
| Symbol(s) | HLA-B | |
| EBI-HLA | B*5501 | |
| B*5502 | ||
| Locus | chr.6 6p21.31 | |
Serotype
B*55:03 is one of the four B alleles that reacts with neither Bw4 nor Bw6. The others are B*18:06, B*46:01, and B*73:01.[2]
| B*55 | B55 | B22 | Sample |
| allele | % | % | size (N) |
| 5501 | 92 | 5 | 453 |
| 5502 | 84 | 2 | 309 |
Allele distribution
| freq | ||
| ref. | Population | (%) |
| [4] | India New Delhi | 3.8 |
| [4] | Singapore Chinese Han | 3.5 |
| [4] | Spain Eastern Andalusia Gipsy | 3.5 |
| [4] | Georgia Tibilisi Kurds | 3.4 |
| [4] | India North Delhi | 3.3 |
| [4] | France South East | 3.1 |
| [4] | Israel Arab Druse | 3.0 |
| [4] | India North Hindus | 2.9 |
| [4] | Georgia Tibilisi Georgians | 2.8 |
| [4] | Russia Tuva (2) | 2.8 |
| [4] | Georgia Svaneti Svans | 2.5 |
| [4] | Iran Baloch | 2.5 |
| [4] | Singapore Thai | 2.5 |
| [4] | Sudanese | 2.5 |
| [4] | Mexico Mestizos | 2.4 |
| [4] | Spain Eastern Andalusia | 2.4 |
| [4] | Ireland South | 2.0 |
| [4] | Azores Central Islands | 1.8 |
| [4] | Bulgaria | 1.8 |
| [4] | Israel Ashkenazi and Non Ashkenazi Jews | 1.8 |
| [4] | Oman | 1.7 |
| [4] | Tunisia Tunis | 1.7 |
| [4] | India Andhra Pradesh Golla | 1.4 |
| [4] | China Tibet | 1.3 |
| [4] | Uganda Kampala | 1.2 |
| [4] | Finland | 1.1 |
| [4] | Portugal North | 1.1 |
| [4] | Portugal Centre | 1.0 |
| [4] | Singapore Riau Malay | 1.0 |
| [4] | B*5502 | |
| [4] | Taiwan Taroko | 14.5 |
| [4] | American Samoa | 12.0 |
| [4] | China Guangxi Maonan | 6.0 |
| [4] | Japan Ainu Hokkaido | 5.0 |
| [4] | China Tibet Autonomous Region Tibetans | 4.7 |
| [4] | Singapore Chinese | 3.0 |
| [4] | China Beijing Shijiazhuang Tianjian Han | 2.9 |
| [4] | China North Han | 2.9 |
| [4] | South Korea (3) | 2.7 |
| [4] | Hong Kong Chinese | 2.2 |
| [4] | Japan (5) | 2.2 |
| [4] | Taiwan Ami | 2.0 |
| [4] | Thailand (3) | 2.0 |
| [4] | New Caledonia | 1.0 |
| [4] | Philippines Ivatan | 1.0 |
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References
- Marsh, S. G.; Albert, E. D.; Bodmer, W. F.; Bontrop, R. E.; Dupont, B.; Erlich, H. A.; Fernández-Viña, M.; Geraghty, D. E.; Holdsworth, R.; Hurley, C. K.; Lau, M.; Lee, K. W.; Mach, B.; Maiers, M.; Mayr, W. R.; Müller, C. R.; Parham, P.; Petersdorf, E. W.; Sasazuki, T.; Strominger, J. L.; Svejgaard, A.; Terasaki, P. I.; Tiercy, J. M.; Trowsdale, J. (2010). "Nomenclature for factors of the HLA system, 2010". Tissue Antigens. 75 (4): 291–455. doi:10.1111/j.1399-0039.2010.01466.x. PMC 2848993. PMID 20356336.
- Voorter, CE; van der Vlies, S; Kik, M; van den Berg-Loonen, EM (October 2000). "Unexpected Bw4 and Bw6 reactivity patterns in new alleles". Tissue Antigens. 56 (4): 363–70. doi:10.1034/j.1399-0039.2000.560409.x. PMID 11098937.
- derived from IMGT/HLA
- Middleton D, Menchaca L, Rood H, Komerofsky R (2003). "New allele frequency database: http://www.allelefrequencies.net". Tissue Antigens. 61 (5): 403–7. doi:10.1034/j.1399-0039.2003.00062.x. PMID 12753660. External link in
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