Geranyl-pyrophosphate—olivetolic acid geranyltransferase
Geranyl-pyrophosphate—olivetolic acid geranyltransferase (EC 2.5.1.102, GOT) is an enzyme with systematic name geranyl-diphosphate:olivetolate geranyltransferase.[1] This enzyme catalyses the following chemical reaction
- geranyl diphosphate + 2,4-dihydroxy-6-pentylbenzoate diphosphate + cannabigerolate
| Geranyl-pyrophosphate—olivetolic acid geranyltransferase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 2.5.1.102 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Part of the cannabinoids biosynthetic pathway of the plant Cannabis sativa.
References
- Fellermeier M, Zenk MH (May 1998). "Prenylation of olivetolate by a hemp transferase yields cannabigerolic acid, the precursor of tetrahydrocannabinol". FEBS Letters. 427 (2): 283–5. doi:10.1016/S0014-5793(98)00450-5. PMID 9607329.
External links
- Geranyl-pyrophosphate---olivetolic+acid+geranyltransferase at the US National Library of Medicine Medical Subject Headings (MeSH)
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