Deserpidine

Deserpidine (INN) is an antihypertensive drug related to reserpine[1] which occurs naturally in Rauvolfia spp.

Deserpidine

Names
IUPAC name methyl (1R,15S,17R,18R,19S,20S)-18-methoxy-17-(3,4,5-trimethoxybenzoyloxy)-3,13-diazapentacyclo[11.8.0.0^2,10.0^4,9.0^15,20]henicosa-2(10),4,6,8-tetraene-19-carboxylate
Identifiers
CAS Number	131-01-1^Y
3D model (JSmol)	Interactive image
ChEBI	CHEBI:27478^Y
ChEMBL	ChEMBL1200515^N
ChemSpider	8232^Y
DrugBank	DB01089^Y
ECHA InfoCard	100.004.551
IUPHAR/BPS	7064
KEGG	D08194^Y
PubChem CID	8550
UNII	9016E3VB47^Y
CompTox Dashboard (EPA)	DTXSID8020383
InChI InChI=1S/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3/t18-,21+,23-,26-,27+,30+/m1/s1^Y Key: CVBMAZKKCSYWQR-WCGOZPBSSA-N^Y InChI=1/C32H38N2O8/c1-37-24-12-17(13-25(38-2)29(24)39-3)31(35)42-26-14-18-16-34-11-10-20-19-8-6-7-9-22(19)33-28(20)23(34)15-21(18)27(30(26)40-4)32(36)41-5/h6-9,12-13,18,21,23,26-27,30,33H,10-11,14-16H2,1-5H3/t18-,21+,23-,26-,27+,30+/m1/s1 Key: CVBMAZKKCSYWQR-WCGOZPBSBL
SMILES O=C(OC)[C@H]6[C@H]4C[C@@H]3c2[nH]c1ccccc1c2CCN3C[C@H]4C[C@@H](OC(=O)c5cc(OC)c(OC)c(OC)c5)[C@@H]6OC
Properties
Chemical formula	C32H38N2O8
Molar mass	578.662 g·mol^−1
Pharmacology
ATC code	C02AA05 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

References

1. Fulton, S. C.; Healy, M. D. (1976). "Comparison of the effectiveness of deserpidine, reserpine, and alpha-methyltyrosine on brain biogenic amines". Federation Proceedings. 35 (14): 2558–2562. PMID 11134.