Mitochondrial glycine transporter

Mitochondrial glycine transporter is a protein that in humans is encoded by the SLC25A38 gene. SLC25A38 is involved in mitochondrial handling of glycine and is needed for the first step in heme synthesis. Mutations in this gene can lead to an autosomal recessive form of sideroblastic anemia.

SLC25A38
Identifiers
Aliases	SLC25A38, SIDBA2, solute carrier family 25 member 38
External IDs	OMIM: 610819 MGI: 2384782 HomoloGene: 5553 GeneCards: SLC25A38
Gene location (Human) Chr. Chromosome 3 (human)[1] Band 3p22.1 Start 39,383,370 bp[1] End 39,397,351 bp[1]
Gene location (Mouse) Chr. Chromosome 9 (mouse)[2] Band 9|9 F4 Start 120,110,374 bp[2] End 120,124,504 bp[2]
Gene ontology Molecular function • glycine transmembrane transporter activity • GO:0022891 transmembrane transporter activity Cellular component • membrane • mitochondrion • mitochondrial inner membrane • integral component of membrane Biological process • heme biosynthetic process • erythrocyte differentiation • mitochondrial transport • transmembrane glycine transport from cytosol to mitochondrion Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	54977	208638
Ensembl	ENSG00000144659	ENSMUSG00000032519
UniProt	Q96DW6	Q91XD8
RefSeq (mRNA)	NM_017875 NM_001354798	NM_144793
RefSeq (protein)	NP_060345 NP_001341727	NP_659042
Location (UCSC)	Chr 3: 39.38 – 39.4 Mb	Chr 9: 120.11 – 120.12 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000144659 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000032519 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.