Uracil dehydrogenase

Uracil dehydrogenase (EC 1.1.99.19, uracil oxidase) is an enzyme with systematic name uracil:(acceptor) oxidoreductase.[1] This enzyme catalyses the following chemical reaction

uracil + acceptor barbiturate + reduced acceptor
Uracil dehydrogenase
Identifiers
EC number1.1.99.19
CAS number9029-00-9
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum

Also oxidizes thymine. The enzyme acts on the hydrated derivative of the substrate.

References

  1. Hayaishi O, Kornberg A (May 1952). "Metabolism of cytosine, thymine, uracil, and barbituric acid by bacterial enzymes". The Journal of Biological Chemistry. 197 (2): 717–32. PMID 12981104.
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