Tetrahydrocortisone

Tetrahydrocortisone, or urocortisone, is a steroid and an inactive metabolite of cortisone.[1]

Tetrahydrocortisone

Names
IUPAC name (3R,5R,8S,9S,10S,13S,14S,17R)-3,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-2,3,4,5,6,7,8,9,12,14,15,16-dodecahydro-1H-cyclopenta[a]phenanthren-11-one
Other names Urocortisone; 3alpha,17,21-Trihydroxypregnane-11,20-dione
Identifiers
CAS Number	53-05-4^N
3D model (JSmol)	Interactive image
ChEMBL	ChEMBL1908043^N
ChemSpider	5657^Y
ECHA InfoCard	100.000.148
PubChem CID	5866
UNII	5HF9TM2D15^Y
CompTox Dashboard (EPA)	DTXSID70878591
InChI InChI=1S/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-15,18,22-23,26H,3-11H2,1-2H3/t12-,13-,14+,15+,18-,19+,20+,21+/m1/s1^Y Key: SYGWGHVTLUBCEM-ZIZPXRJBSA-N^Y InChI=1/C21H32O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h12-15,18,22-23,26H,3-11H2,1-2H3/t12-,13-,14+,15+,18-,19+,20+,21+/m1/s1 Key: SYGWGHVTLUBCEM-ZIZPXRJBBU
SMILES O=C2[C@H]3[C@H]([C@@H]1CC[C@](O)(C(=O)CO)[C@@]1(C)C2)CC[C@@H]4C[C@H](O)CC[C@]34C
Properties
Chemical formula	C21H32O5
Molar mass	364.48 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N verify (what is ^YN ?)
Infobox references

See also

• Tetrahydrocortisol
• Tetrahydrocorticosterone

References

1. Thomas L. Lemke; David A. Williams (24 January 2012). Foye's Principles of Medicinal Chemistry. Lippincott Williams & Wilkins. pp. 915–. ISBN 978-1-60913-345-0.