NAT8

N-acetyltransferase 8 is a protein that in humans is encoded by the NAT8 gene.[5]

NAT8
Identifiers
AliasesNAT8, ATase2, CML1, GLA, Hcml1, TSC501, TSC510, CCNAT, N-acetyltransferase 8 (putative)
External IDsOMIM: 606716 MGI: 1915646 HomoloGene: 9479 GeneCards: NAT8
EC number2.3.1.80
Gene location (Human)
Chr.Chromosome 2 (human)[1]
Band2p13.1Start73,640,723 bp[1]
End73,642,422 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

9027

68396

Ensembl

ENSG00000144035

ENSMUSG00000030004

UniProt

Q9UHE5

Q9JIY7

RefSeq (mRNA)

NM_003960

NM_023455
NM_001362060

RefSeq (protein)

NP_003951

NP_075944
NP_001348989

Location (UCSC)Chr 2: 73.64 – 73.64 MbChr 6: 85.83 – 85.83 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Clinical relevance

Mutations in the NAT8 gene have been associated with chronic kidney disease.[6]

gollark: ```python#!/bin/env python3chars = [chr(n) for n in range(126)]firstchar = chars[0]lastchar = chars[len(chars) - 1]def increment_char(character): return chr(ord(character) + 1)def old_increment_string(string_to_increment): reversed_string = list(reversed(string_to_increment)) # Reverse the string for easier work. for rindex, char in enumerate(reversed_string): if char == lastchar: # If we can't increment this char further, try the next ones. reversed_string[rindex] = firstchar # Set the current char back to the first one. reversed_string[rindex + 1] = increment_char(reversed_string[rindex + 1]) # Increment the next one along. else: # We only want to increment ONE char, unless we need to "carry". reversed_string[rindex] = increment_char(reversed_string[rindex]) break return ''.join(list(reversed(reversed_string)))def increment_string(to_increment): reversed_string = list(to_increment) # Reverse the string for easier work. for rindex, char in enumerate(reversed_string): if char == lastchar: # If we can't increment this char further, try the next ones. reversed_string[rindex] = firstchar # Set the current char back to the first one. reversed_string[rindex + 1] = increment_char(reversed_string[rindex + 1]) # Increment the next one along. else: # We only want to increment ONE char, unless we need to "carry". reversed_string[rindex] = increment_char(reversed_string[rindex]) break return ''.join(list(reversed_string))def string_generator(): length = 0 while 1: length += 1 string = chars[0] * length while True: try: string = increment_string(string) except IndexError: # Incrementing has gone out of the char array, move onto next length break yield string```
gollark: Except it enumerates all possible ASCII strings instead.
gollark: I made that!
gollark: no.
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References
  1. GRCh38: Ensembl release 89: ENSG00000144035 - Ensembl, May 2017
  2. GRCm38: Ensembl release 89: ENSMUSG00000030004 - Ensembl, May 2017
  3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. "Entrez Gene: N-acetyltransferase 8 (GCN5-related".
  6. Suhre K, Shin SY, Petersen AK, Mohney RP, Meredith D, Wägele B, Altmaier E, Deloukas P, Erdmann J, Grundberg E, Hammond CJ, de Angelis MH, Kastenmüller G, Köttgen A, Kronenberg F, Mangino M, Meisinger C, Meitinger T, Mewes HW, Milburn MV, Prehn C, Raffler J, Ried JS, Römisch-Margl W, Samani NJ, Small KS, Wichmann HE, Zhai G, Illig T, Spector TD, Adamski J, Soranzo N, Gieger C (September 2011). "Human metabolic individuality in biomedical and pharmaceutical research". Nature. 477 (7362): 54–60. doi:10.1038/nature10354. PMC 3832838. PMID 21886157.

Further reading
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