Fuculose

Fuculose or 6-deoxy-tagatose is a ketohexose deoxy sugar.[1][2] Fuculose is involved in the process of sugar metabolism.[3] It is both a human and Escherichia coli metabolite and catalyzes the production of dihydroxyacetone phosphate(DHAP).[4]

l-Fuculose

Names
IUPAC name (3R,4S,5S)-2-(Hydroxymethyl)-5-methyltetrahydrofuran-2,3,4-triol
Other names 6-Deoxy-l-tagatose
Identifiers
CAS Number	13074-08-3^Y
3D model (JSmol)	Interactive image
PubChem CID	6857362
CompTox Dashboard (EPA)	DTXSID30926880
SMILES O[C@H]1[C@@H](O)C(O)(CO)O[C@H]1C
Properties
Chemical formula	C6H12O5
Molar mass	164.16 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

See also

• l-fuculose-phosphate aldolase
• l-fuculosekinase

References

1. Lindhorst TK (2007). Essentials of Carbohydrate Chemistry and Biochemistry (1 ed.). Wiley-VCH. ISBN 3-527-31528-4.
2. Robyt JF (1997). Essentials of Carbohydrate Chemistry (1st ed.). Springer. ISBN 0-387-94951-8.
3. Wen L, Zang L, Huang K, Li S, Wang R, Wang PG (February 2016). "Efficient enzymatic synthesis of L-rhamnulose and L-fuculose". Bioorganic & Medicinal Chemistry Letters. 26 (3): 969–972. doi:10.1016/j.bmcl.2015.12.051. PMC 5984655. PMID 26778148.
4. Joerger AC, Gosse C, Fessner WD, Schulz GE (May 2000). "Catalytic action of fuculose 1-phosphate aldolase (class II) as derived from structure-directed mutagenesis". Biochemistry. 39 (20): 6033–41. doi:10.1021/bi9927686. PMID 10821675.