KIAA0460

Regulation of nuclear pre-mRNA domain-containing protein 2 is a protein that in humans is encoded by the RPRD2 gene.[5][6]

RPRD2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4FLB
Identifiers
Aliases	RPRD2, KIAA0460, HSPC099, regulation of nuclear pre-mRNA domain containing 2
External IDs	OMIM: 614695 MGI: 1922387 HomoloGene: 19997 GeneCards: RPRD2
Gene location (Human) Chr. Chromosome 1 (human)[1] Band 1q21.2 Start 150,363,091 bp[1] End 150,476,566 bp[1]
Gene location (Mouse) Chr. Chromosome 3 (mouse)[2] Band 3|3 F2.1 Start 95,760,341 bp[2] End 95,818,863 bp[2]
Gene ontology Molecular function • RNA polymerase II core binding Cellular component • DNA-directed RNA polymerase II, holoenzyme • nucleoplasm Biological process • snRNA transcription from RNA polymerase II promoter • mRNA 3'-end processing Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23248	75137
Ensembl	ENSG00000163125	ENSMUSG00000028106
UniProt	Q5VT52	Q6NXI6
RefSeq (mRNA)	NM_001297673 NM_001297674 NM_015203	NM_001081293 NM_028328 NM_029180 NM_001368178 NM_001368179 NM_001368180 NM_001368181
RefSeq (protein)	NP_001284602 NP_001284603 NP_056018	NP_001074762 NP_001355107 NP_001355108 NP_001355109 NP_001355110 NP_082604
Location (UCSC)	Chr 1: 150.36 – 150.48 Mb	Chr 3: 95.76 – 95.82 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

References

1. GRCh38: Ensembl release 89: ENSG00000163125 - Ensembl, May 2017
2. GRCm38: Ensembl release 89: ENSMUSG00000028106 - Ensembl, May 2017
3. "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
4. "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
5. Seki N, Ohira M, Nagase T, Ishikawa K, Miyajima N, Nakajima D, Nomura N, Ohara O (Feb 1998). "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain". DNA Res. 4 (5): 345–9. doi:10.1093/dnares/4.5.345. PMID 9455484.
6. "Entrez Gene: KIAA0460 KIAA0460".

Further reading

• Nakajima D, Okazaki N, Yamakawa H, et al. (2003). "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones". DNA Res. 9 (3): 99–106. doi:10.1093/dnares/9.3.99. PMID 12168954.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Lehner B, Sanderson CM (2004). "A Protein Interaction Framework for Human mRNA Degradation". Genome Res. 14 (7): 1315–23. doi:10.1101/gr.2122004. PMC 442147. PMID 15231747.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Gregory SG, Barlow KF, McLay KE, et al. (2006). "The DNA sequence and biological annotation of human chromosome 1". Nature. 441 (7091): 315–21. doi:10.1038/nature04727. PMID 16710414.
• Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243.
• Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

External links

• PDBe-KB provides an overview of all the structure information available in the PDB for Human Regulation of nuclear pre-mRNA domain-containing protein 2 (KIAA0460)