Hexose oxidase
In enzymology, a hexose oxidase (EC 1.1.3.5) is an enzyme that catalyzes the chemical reaction
- D-glucose + O2 D-glucono-1,5-lactone + H2O2
hexose oxidase | |||||||||
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Identifiers | |||||||||
EC number | 1.1.3.5 | ||||||||
CAS number | 9028-75-5 | ||||||||
Databases | |||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB structures | RCSB PDB PDBe PDBsum | ||||||||
Gene Ontology | AmiGO / QuickGO | ||||||||
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Thus, the two substrates of this enzyme are D-glucose and O2, whereas its two products are D-glucono-1,5-lactone and H2O2.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. The systematic name of this enzyme class is D-hexose:oxygen 1-oxidoreductase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, copper.
References
- BEAN RC, HASSID WZ (1956). "Carbohydrate oxidase from A red alga, Iridophycus flaccidum". J. Biol. Chem. 218 (1): 425–36. PMID 13278350.
- BEAN RC, PORTER GG, STEINBERG BM (1961). "Carbohydrate metabolism of citrus fruits. II. Oxidation of sugars by an aerodehydrogenase from young orange fruits". J. Biol. Chem. 236: 1235–40. PMID 13688220.
- Sullivan JD, Ikawa M (1973). "Purification and characterization of hexose oxidase from the red alga Chondrus crispus". Biochim. Biophys. Acta. 309 (1): 11–22. doi:10.1016/0005-2744(73)90312-4. PMID 4708670.
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