Glucose dehydrogenase (acceptor)
In enzymology, a glucose dehydrogenase (acceptor) (EC 1.1.99.10) is an enzyme that catalyzes the chemical reaction
- D-glucose + acceptor D-glucono-1,5-lactone + reduced acceptor
| glucose dehydrogenase (acceptor) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.99.10 | ||||||||
| CAS number | 37250-84-3 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
Thus, the two substrates of this enzyme are D-glucose and acceptor, whereas its two products are D-glucono-1,5-lactone and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-glucose:acceptor 1-oxidoreductase. Other names in common use include glucose dehydrogenase (Aspergillus), glucose dehydrogenase (decarboxylating), and D-glucose:(acceptor) 1-oxidoreductase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, FAD.
References
- Bak TG (July 1967). "Studies on glucose dehydrogenase of Aspergillus oryzae. II. Purification and physical and chemical properties". Biochimica et Biophysica Acta (BBA) - Enzymology. 139 (2): 277–93. doi:10.1016/0005-2744(67)90032-0. PMID 6034674.
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