Galactitol 2-dehydrogenase

In enzymology, a galactitol 2-dehydrogenase (EC 1.1.1.16) is an enzyme that catalyzes the chemical reaction

galactitol + NAD+ D-tagatose + NADH + H+
galactitol 2-dehydrogenase
Identifiers
EC number1.1.1.16
CAS number9028-23-3
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are galactitol and NAD+, whereas its 3 products are D-tagatose, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is galactitol:NAD+ 2-oxidoreductase. This enzyme is also called dulcitol dehydrogenase. This enzyme participates in galactose metabolism.

References

    • Shaw DR (November 1956). "Polyol dehydrogenases. 3. Galactitol dehydrogenase and D-iditol dehydrogenase". The Biochemical Journal. 64 (3): 394–405. PMC 1199749. PMID 13373783.


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